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- Title
Refined 4‐group classification of left ventricular hypertrophy based on ventricular concentricity and volume dilatation outlines distinct noninvasive hemodynamic profiles in a large contemporary echocardiographic population.
- Authors
Barbieri, Andrea; Rossi, Andrea; Gaibazzi, Nicola; Erlicher, Andrea; Mureddu, Gian Francesco; Frattini, Silvia; Faden, Giacomo; Manicardi, Marcella; Beraldi, Monica; Agostini, Francesco; Lazzarini, Valentina; Moreo, Antonella; Temporelli, Pier Luigi; Faggiano, Pompilio
- Abstract
Background: Left ventricular hypertrophy (LVH) may reflect a wide variety of physiologic and pathologic conditions. Thus, it can be misleading to consider all LVH to be homogenous or similar. Refined 4‐group classification of LVH based on ventricular concentricity and dilatation may be identified. To determine whether the 4‐group classification of LVH identified distinct phenotypes, we compared their association with various noninvasive markers of cardiac stress. Methods: Cohort of unselected adult outpatients referred to a seven tertiary care echocardiographic laboratory for any indication in a 2‐week period. We evaluated the LV geometric patterns using validated echocardiographic indexation methods and partition values. Results: Standard echocardiography was performed in 1137 consecutive subjects, and LVH was found in 42%. The newly proposed 4‐group classification of LVH was applicable in 88% of patients. The most common pattern resulted in concentric LVH (19%). The worst functional and hemodynamic profile was associated with eccentric LVH and those with mixed LVH had a higher prevalence of reduced EF than those with concentric LVH (P < .001 for all). Conclusions: The new 4‐group classification of LVH system showed distinct differences in cardiac function and noninvasive hemodynamics allowing clinicians to distinguish different LV hemodynamic stress adaptations in patients with LVH.
- Subjects
LEFT heart ventricle; HEMODYNAMICS; POPULATION; VENTRICULAR remodeling; TERTIARY care; LEFT ventricular hypertrophy; DIAGNOSIS; ANATOMY
- Publication
Echocardiography, 2018, Vol 35, Issue 9, p1258
- ISSN
0742-2822
- Publication type
Article
- DOI
10.1111/echo.14031