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- Title
Rebuttal from Florian Lang and Else K. Hoffmann.
- Authors
Lang, Florian; Hoffmann, Else K.
- Abstract
The article presents a rebuttal from researchers Florian Lang and Else K. Hoffman about their study on cell volume changes during apoptosis. They note that the commentary was focused on three issues, the failure to detect early shrinkage during apoptosis, decrease in intracellular ion concentration and hyperosmotic shrinkage. The claim that the involve signalling pathways can be activated by other mechanisms thus making apoptotic volume decrease (AVD) dispensable.
- Subjects
APOPTOSIS; CELL size; CYTOLOGY; CELL death; BACTERIOLYSIS
- Publication
Journal of Physiology, 2013, Vol 591, Issue 24, p6127
- ISSN
0022-3751
- Publication type
Article
- DOI
10.1113/jphysiol.2013.265231