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- Title
IN-VITRO EVALUATION OF POTENCY OF BRANDS OF CO-ARTEMISININ AGAINST Plasmodium falciparum STRAINS IN KANO, NIGERIA.
- Authors
Hadiza, A. M.; Mukthar, M. D.; Taura, D. W.
- Abstract
The short term in-vitro growth of plasmodium falciparum in asexual erythrocyte stage and the in-vitro activities of fourteen different standard artemisinin combination antimalarial drugs bought in duplicates were assessed and compared using the Roswell park memorial institute media (RPMI 1640) medium supplemented with 10% rabbit serum. The test shows that about 80% 0f the drugs were active in-vitro against P. falciparum. No statistical significant difference was observed in terms of antiplasmodial activities between the open market brands and the brands bought from the pharmacy within the prescribed shelf life of the drugs.
- Subjects
PLASMODIUM falciparum; ARTEMISININ; IN vitro studies; ERYTHROCYTE disorders; ANTIFIBRINOLYTIC agents; PREVENTION; THERAPEUTICS
- Publication
Bayero Journal of Pure & Applied Sciences, 2017, Vol 10, p331
- ISSN
2006-6996
- Publication type
Article
- DOI
10.4314/bajopas.v10i1.66S