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- Title
Successful treatment of disseminated fusariosis with voriconazole in an acute lymphoblastic leukaemia patient.
- Authors
Labois, Aurelie; Gray, Christian; Lepretre, Stephane
- Abstract
Summary Fusarium species are actually the second most common pathogenic mould in immunocompromised patients, and it is difficult to treat such fusarial infections with current antifungal agents. We report the case of a 53-year-old woman with Philadelphia-positive acute lymphoblastic leukaemia. During induction chemotherapy with febrile neutropenia, she developed a disseminated fusariosis, with persistent fever refractory to antibacterial agents and caspofungin (as empirical therapy), painful skin lesions and respiratory impairment. Fusarium solani was isolated from skin biopsy. Voriconazole was successfully implemented as antifungal curative therapy. During the second intensive chemotherapy no reactivation of fusariosis was detected.
- Subjects
CASE studies; FUSARIUM; LYMPHOBLASTIC leukemia; ANTIFUNGAL agents; DRUG therapy; PATIENTS
- Publication
Mycoses, 2011, Vol 54, p8
- ISSN
0933-7407
- Publication type
Article
- DOI
10.1111/j.1439-0507.2011.02136.x