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- Title
Digital cervicography-directed cervical biopsy in women with abnormal cervical cytology.
- Authors
Tae Jin Kim; So, Kyeong A.; Eunbi Jang; Jin Lee, A.; Seung-Hyuk Shim; Sun Joo Lee
- Abstract
Objective: Digital cervicography (DC) is a cervical cancer screening method that involves the application of acetic acid and subsequent capture of images for analysis. DC presents several advantages, including visual capabilities comparable to colposcopy for observing the squamous column junction, abnormal cervical shape, and blood vessels. This study aimed to evaluate the clinical performance of cervicography-directed biopsy in detecting cervical intraepithelial neoplasia (CIN) and cervical cancer in women with abnormal cervical cytology. Methods: This retrospective study included women with abnormal cervical cytology who underwent cervicographydirected biopsy between 2019 and 2023 at a tertiary medical center in South Korea. Clinicopathologic data including age, cervical cytology, and histologic grade were collected. After the application of 5% acetic acid to the cervix, changes in the cervix are observed using DC, and a cervical biopsy of the lesion is performed. The agreement rate between the results of cervical cytology and cervicography-directed biopsy was analyzed. Results: A total of 200 women were enrolled. The overall agreement between the findings of cervical cytology and the histology results for cervicography-directed biopsy was 77.5%. When analyzing the agreement rate by group, it was 70% in the ASC-US/LSIL group, 90.5% in the ASC-H/HSIL group, and 100% in the SCC group. The diagnostic rate of high-grade CIN and cervical cancer utilizing cervicography-directed biopsy in women with ASC-H/HISL was 91.4%. Conclusion: In patients with abnormal cervical cytology, cervicography-directed biopsy is useful for diagnosing high-grade CIN and cervical cancer.
- Subjects
SOUTH Korea; COLPOSCOPY; CYTOLOGY; CERVICAL intraepithelial neoplasia; BIOPSY; CERVICAL cancer; ACETIC acid; EARLY detection of cancer
- Publication
Journal of Gynecologic Oncology, 2024, Vol 35, p50
- ISSN
2005-0380
- Publication type
Article
- DOI
10.3802/jgo.2024.35.S2.P59