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- Title
Incidence and risk factors for insufficient endometrial tissue from endometrial sampling.
- Authors
Aue-aungkul, Apiwat; Kleebkaow, Pilaiwan; Kietpeerakool, Chumnan
- Abstract
Objective: To assess the incidence of and factors that predict insufficient tissue after endometrial sampling. Methods: This study reviewed the records of women undergoing endometrial sampling at Khon Kaen University’s Srinagarind Hospital between June 2014 and June 2015. It excluded cases in which the device could not be inserted into the uterine cavity due to pain intolerance or equipment failure. The criterion for diagnosing insufficient endometrial tissue was a lack of any intact tissue fragments containing both glands and stroma. Results: Medical records of 233 women were reviewed. Insufficient tissue following endometrial sampling was noted in 67 cases (28.8%; 95% confidence interval [CI]=23.0–35.0). Histologic results in the remaining 166 women included normal pathological endometrium (121, 51.9%), endometrial polyps (7, 3.0%) endometrial hyperplasia (27, 11.6%), and endometrial cancer (11, 4.7%). According to multivariable analysis, menopausal status (odds ratio [OR] =3.60, 95% CI=1.84–7.05) and endometrial thickness of less than 8 mm (OR=3.91, 95% CI=1.49–10.21) were significant independent predictors for insufficient endometrial tissue after endometrial sampling. Conclusion: The incidence of insufficient tissue following endometrial sampling was 28.8%. Significant independent factors associated with an increased risk of insufficient tissue were menopausal status and endometrial thickness of less than 8 mm.
- Subjects
ENDOMETRIOSIS; ENDOMETRIAL biopsy; FACTOR analysis; MULTIVARIABLE testing; POSTMENOPAUSE; THERAPEUTICS; DISEASE risk factors
- Publication
International Journal of Women's Health, 2018, Vol 10, p453
- ISSN
1179-1411
- Publication type
Article
- DOI
10.2147/IJWH.S172696