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- Title
直立倾斜试验不同时间点心率和心率差对儿童及青少年体位性心动过速综合征的诊断效率.
- Authors
王硕; 邹润梅; 蔡虹; 丁异熠; 肖海辉; 王欣; 李芳; 王玉汶; 王成
- Abstract
Objective To study the efficiency of heart rate (HR) and heart rate difference (HRD) at different time points during head-up tilt test (HUTT) in the diagnosis of postural tachycardia syndrome (POTS) in children and adolescents. Methods A total of 217 children and adolescents, aged 6-16 years, who were diagnosed with POTS were enrolled as the POTS group, and 73 healthy children and adolescents, matched for sex and age, were enrolled as the control group. The POTS group was further divided into ≤ 12 years old group with 127 children/adolescents and > 12 years old group with 90 children/adolescents. The two groups were compared in terms of HR at baseline and at 5 and 10 minutes of HUTT (HR0, HR5, and HR10 respectively), difference between HR5/HR10 and HR0 (HRD5 and HRD10 respectively). The efficiency of HR5, HR10, HRD5 and HRD10 in the diagnosis of POTS was assessed. Results Compared with the control group, the POTS group had significant increases in HR5, HR10, HRD5, and HRD10 (P < 0.05). The coincidence rate of HR or HRD for the diagnosis of POTS in males was higher than that in females at 5 minutes of HUTT (P < 0.05), while the coincidence rate of HR or HRD for the diagnosis of POTS in males was lower than that in females at 10 minutes of HUTT (P < 0.05). The coincidence rate of HR for the diagnosis of POTS was higher in the > 12 years old subgroup (P < 0.05), while the coincidence rate of HRD for the diagnosis of POTS was higher in the ≤ 12 years old subgroup (P < 0.05). The combination of HR5, HR10, HRD5, and HRD10 for the diagnosis of POTS had a greater area under the curve (0.974; 95% CI:0.949-0.989) than HR5, HR10, HRD5, or HRD10 alone, with a sensitivity of 87.80% and a specificity of 95.83%. The diagnostic efficacy of HRD for POTS was higher than that of HR (P < 0.05). Conclusions HR and HRD at different time points during HUTT have a good value in the diagnosis of POTS in children and adolescents, and the accuracy of diagnosis varies with age and gender.
- Subjects
HEART beat; TILT-table test; TEENAGERS; COINCIDENCE; POTS
- Publication
Chinese Journal of Contemporary Pediatrics, 2020, Vol 22, Issue 7, p780
- ISSN
1008-8830
- Publication type
Article
- DOI
10.7499/j.issn.1008-8830.2003133