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- Title
Cancer and Cardiovascular Disease: The Conjoined Twins.
- Authors
Zmaili, Mohammad; Alzubi, Jafar; Alkhayyat, Motasem; Albakri, Almaza; Alkhalaileh, Feras; Longinow, Joshua; Moudgil, Rohit
- Abstract
Simple Summary: Cardiovascular disease and cancer are two major causes of morbidity and mortality worldwide. The significant overlap between cardiovascular medicine and oncology led to the emergence of the cardio-oncology field. Understanding the pathophysiological basis of the interconnected relationship between cardiovascular disease and cancer is fundamental to improving patient care and clinical outcomes. Several cardiovascular therapies have proven beneficial in the oncologic field, and thus, may need to be incorporated into the therapeutic armamentarium against cancer. Cancer and cardiovascular disease are the two most common causes of death worldwide. As the fields of cardiovascular medicine and oncology continue to expand, the area of overlap is becoming more prominent demanding dedicated attention and individualized patient care. We have come to realize that both fields are inextricably intertwined in several aspects, so much so that the mere presence of one, with its resultant downstream implications, has an impact on the other. Nonetheless, cardiovascular disease and cancer are generally approached independently. The focus that is granted to the predominant pathological entity (either cardiovascular disease or cancer), does not allow for optimal medical care for the other. As a result, ample opportunities for improvement in overall health care are being overlooked. Herein, we hope to shed light on the interconnected relationship between cardiovascular disease and cancer and uncover some of the unintentionally neglected intricacies of common cardiovascular therapeutics from an oncologic standpoint.
- Subjects
TUMOR risk factors; CARDIOVASCULAR disease prevention; TUMOR prevention; CARDIOVASCULAR diseases; EXERCISE; ASPIRIN; ACE inhibitors; CARDIO-oncology; CARDIOVASCULAR diseases risk factors; CANCER patients; CALCIUM antagonists; ANGIOTENSIN receptors; ADRENERGIC beta blockers; STATINS (Cardiovascular agents); SODIUM-glucose cotransporter 2 inhibitors; TUMORS; INFLAMMATION; MEDICAL screening
- Publication
Cancers, 2024, Vol 16, Issue 8, p1450
- ISSN
2072-6694
- Publication type
Article
- DOI
10.3390/cancers16081450