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- Title
Many mini mind promoters.
- Authors
de Souza, Natalie
- Abstract
The article focuses on the project, called Pleiades Promoter Project, in which a group of scientists are working to design mini promoters (MiniPs), the short constructs of human DNA sequence that drive restricted gene expression in the mouse brain. It states that the tools to target restricted gene expression are helpful in the study of how a tissue functions or is organized. It describes how the team tested several MiniPs for their ability to drive gene expression in the brain of adult mouse.
- Subjects
PROMOTERS (Genetics); GENE expression; NUCLEOTIDE sequence; GENETIC regulation; BRAIN research
- Publication
Nature Methods, 2010, Vol 7, Issue 11, p870
- ISSN
1548-7091
- Publication type
Article
- DOI
10.1038/nmeth1110-870b