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- Title
Sustainable approach to manage the vulnerable rodents using eco-friendly green rodenticides formulation through nanotechnology principles – A review.
- Authors
Karthick Raja Namasivayam, S.; Srinivasan, Subramanian; Samrat, Krishnappa; Priyalakshmi, Bala; Dinesh Kumar, Ramkumar; Bharani, Arvind; Ganesh Kumar, Ramkumar; Kavisri, M.; Moovendhan, Meivelu
- Abstract
This review provides an insight into the nanotechnology principles for plant-based rodenticides formulation and how they can be developed and superior to the conventional rodent control program. Development of Phyto or green nano rodenticides involves the selection of plant material, extraction of rodenticidal metabolites, formulation of plant extracts as Nanoparticles (Polymeric, Nanocapsules, Nanospheres, Solid, Lipid), Nanoemulsion, Nanocomposite, Nanoliposomes via green science or green technology principles, characterisation of nanoformulation like morphology, surface topology, functional group determination using electron microscopy, spectroscopy and X-ray crystallography. The effectiveness of the nanosystem can be proved by the determination of loading, entrapment efficacy and release profile. Bioassays studies with the respective nanoformulation under laboratory and field trials tests reveal Nanorodenticides. The stability of the respective nanoparticulate formulation can be assessed by zeta potential measurement. After the successful validation, it is necessary to study biocompatibility or biosafety using a suitable in vitro and in vivo screening model system that can be assessed through cell lines and zebrafish models. Any sign of toxic effect that can be measured in the respective model system reveals outstanding biocompatibility. This review demonstrates that the Nano Phyto rodenticides formulated by green nanotechnology can be potentially used to control rodents in an eco-friendly manner with high efficacy. [Display omitted]
- Subjects
RODENTICIDES; GREEN technology; NANOTECHNOLOGY; X-ray crystallography; POISONS; RODENT control; ZETA potential
- Publication
Process Safety & Environmental Protection: Transactions of the Institution of Chemical Engineers Part B, 2023, Vol 171, p591
- ISSN
0957-5820
- Publication type
Article
- DOI
10.1016/j.psep.2023.01.050