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- Title
Using probiotics in paediatric populations.
- Authors
Schneider, Rilla; Sant'Anna, Ana
- Abstract
This statement defines probiotics and reviews the most recent literature on their use in paediatrics. Many studies have examined the potential benefit of probiotics, but significant variation in the strains and doses of probiotics used, the patient populations studied, and in study design, have led to heterogeneous results. Present evidence suggests that probiotics can decrease mortality and lower incidence of necrotizing enterocolitis in preterm and low birth weight neonates. Probiotics may also be beneficial in reducing feeding intolerance. In infants, probiotics may be considered to reduce symptoms of colic. In older children, probiotics can be considered to prevent antibiotic-associated diarrhea and Clostridium difficile -associated diarrhea. Probiotic supplements used in conjunction with standard therapy can help with Helicobacter pylori eradication and decrease the side effects of treatment. Lactobacillus species can be considered to treat irritable bowel syndrome. Probiotics can also be considered to help prevent atopic dermatitis and eczema. To optimize paediatric policy and practice, large, quality studies are needed to determine what types and combinations of probiotics are most efficacious.
- Subjects
CANADA; THERAPEUTIC use of probiotics; DIARRHEA prevention; DRUG efficacy; NEONATAL necrotizing enterocolitis; INFLAMMATORY bowel diseases; ECZEMA; FOOD intolerance; PEDIATRICS; INFANTILE colic; PROBIOTICS; LOW birth weight; CLOSTRIDIUM diseases; DIETARY supplements; MEDICAL protocols; DOSE-effect relationship in pharmacology; ATOPIC dermatitis; DEATH; LACTOBACILLUS; ANTIBIOTICS; HELICOBACTER diseases; EVALUATION; DISEASE complications; CHILDREN
- Publication
Paediatrics & Child Health (1205-7088), 2022, Vol 27, Issue 8, p482
- ISSN
1205-7088
- Publication type
Article
- DOI
10.1093/pch/pxac087