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- Title
Epidemiology of progressive supranuclear palsy.
- Authors
Vanacore, N.; Bonifati, V.; Colosimo, C.; Fabbrini, G.; De Michele, G.; Marconi, R.; Nicholl, D.; Locuratolo, N.; Romano, S.; Talarico, G.; Stocchi, F.; Bonuccelli, U.; Lamberti, P.; Vieregge, P.; Meco, G.
- Abstract
Progressive supranuclear palsy (PSP) is a rare form of parkinsonism. The incidence rates are about 0.3–1.1 cases per 100 000 persons. The only two-case-control studies performed up to now show conflictual results as regards education and residence in rural areas. Recently, a cluster of PSP and atypical parkinsonism has been observed in French Antilles. The hypothesis is that a consumption of both tropical fruit and herbal tea may be associated with PSP onset. Some PSP families with a probably autosomal dominant transmission have been described. A high frequency of a tau haplotype (H[sub 1] /H[sub 1] ) associated with PSP is reported by some authors. The significance of this association is still not clear. We have performed a case-control study on 58 PSP cases, 116 hospital controls and 58 population controls.
- Subjects
PROGRESSIVE supranuclear palsy; DEMENTIA; PARKINSON'S disease
- Publication
Neurological Sciences, 2001, Vol 22, Issue 1, p101
- ISSN
1590-1874
- Publication type
Article
- DOI
10.1007/s100720170065