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- Title
Association of exercise with all-cause mortality in older Taipei residents.
- Authors
Lai, Yun-Ju; Yen, Yung-Feng; Chen, Li-Jung; Ku, Po-Wen; Chen, Chu-Chieh; Lin, Yu-Kai
- Abstract
Background Human life expectancy has increased rapidly in recent decades. Regular exercise can promote health, but the effect of exercise on mortality is not yet well understood. Objective To investigate the association of exercise with mortality in the older people. Methods We used data from annual health check-ups of the older citizens of Taipei in 2006. Participants were interviewed by trained nurses using a structured questionnaire to collect data on demographics and lifestyle behaviours. Overnight fasting blood was collected for measuring blood glucose, liver and renal function and lipid profiles. Exercise frequency was categorised into no exercise, 1–2 times in a week and more than 3–5 times in a week. All-cause mortality was ascertained from the National Registration of Death. All participants were followed up until death or December 312012, whichever came first. Kaplan–Meier curves and Cox proportional hazard analysis were used to investigate the association between exercise and all-cause mortality. Results In total, 42,047 older people were analysed; 22,838 (54.32%) were male and with a mean (SD) age of 74.58 (6.32) years. Kaplan–Meier curves of all-cause mortality stratified by exercise frequency demonstrated significant findings (Log-rank P < 0.01). Multivariate Cox regression analysis showed that older people with higher exercise levels had a significantly decreased risk of mortality (moderate exercise HR = 0.74, 95% CI: 0.68–0.81, high exercise HR = 0.65, 95% CI: 0.59–0.70) after adjusting for potential confounders, with a significant trend (P for trend<0.01). Conclusions Older people with increased exercise levels had a significantly decreased risk of all-cause mortality.
- Subjects
TAIWAN; BLOOD sugar analysis; MORTALITY prevention; MORTALITY risk factors; CONFIDENCE intervals; EXERCISE; FASTING; INTERVIEWING; KIDNEY function tests; LIPIDS; LIVER function tests; NURSES; LIFESTYLES; PROPORTIONAL hazards models; KAPLAN-Meier estimator; ODDS ratio; OLD age
- Publication
Age & Ageing, 2020, Vol 49, Issue 3, p382
- ISSN
0002-0729
- Publication type
Article
- DOI
10.1093/ageing/afz172