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- Title
Body mass index and remote ischaemic conditioning efficacy in acute ischaemic stroke patients: A post hoc analysis of the Remote Ischaemic Conditioning for Acute Moderate Ischaemic Stroke (RICAMIS) trial.
- Authors
Sun, Xiao‐Yu; Qu, Hui‐Ling; Chen, Hui‐Sheng
- Abstract
This article discusses the impact of body mass index (BMI) on the efficacy of remote ischaemic conditioning (RIC) in acute ischaemic stroke patients. The study found that RIC was associated with improved functional outcomes in patients with normal weight, but not in overweight or obese patients. The results suggest that the protective effect of RIC may be influenced by BMI, and further research is needed to understand the effects of obesity on RIC. However, a post hoc analysis of the same trial found that BMI did not affect the efficacy of RIC, and RIC treatment was associated with excellent clinical outcomes in patients with normal weight. The study suggests that RIC is appropriate for overweight and obese patients with acute ischemic stroke, but more research is needed to confirm these findings in other populations.
- Subjects
ISCHEMIC stroke; BODY mass index; ISCHEMIC conditioning; STROKE patients; CEREBRAL arteries; OBESITY paradox; REPERFUSION; BLOOD-brain barrier
- Publication
Diabetes, Obesity & Metabolism, 2024, Vol 26, Issue 7, p2993
- ISSN
1462-8902
- Publication type
Article
- DOI
10.1111/dom.15614