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Coexistence of passive and carrier-mediated processes in drug transport.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Acamprosate Is a Substrate of the Human Organic Anion Transporter (OAT) 1 without OAT3 Inhibitory Properties: Implications for Renal Acamprosate Secretion and Drug–Drug Interactions.
- Published in:
- Pharmaceutics, 2020, v. 12, n. 4, p. 390, doi. 10.3390/pharmaceutics12040390
- By:
- Publication type:
- Article
Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane.
- Published in:
- Journal of Neuroscience, 2023, v. 43, n. 13, p. 2222, doi. 10.1523/JNEUROSCI.1519-22.2022
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- Publication type:
- Article
Hepatic Expression of the Na + -Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 7468, doi. 10.3390/ijms23137468
- By:
- Publication type:
- Article
Professor Margareta Hammarlund-Udenaes - Humbled Scientist Shaping Modern Neuropharmacokinetics.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 7, p. 1283, doi. 10.1007/s11095-022-03279-x
- By:
- Publication type:
- Article
High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 7, p. 1599, doi. 10.1007/s11095-022-03171-8
- By:
- Publication type:
- Article
A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f<sub>u,cell</sub>).
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 12, p. N.PAG, doi. 10.1007/s11095-019-2717-1
- By:
- Publication type:
- Article
The Critical Role of Passive Permeability in Designing Successful Drugs.
- Published in:
- ChemMedChem, 2020, v. 15, n. 20, p. 1862, doi. 10.1002/cmdc.202000419
- By:
- Publication type:
- Article
Hepatocyte size fractionation allows dissection of human liver zonation.
- Published in:
- Journal of Cellular Physiology, 2021, v. 236, n. 8, p. 5885, doi. 10.1002/jcp.30273
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- Publication type:
- Article
Intracellular drug bioavailability: a new predictor of system dependent drug disposition.
- Published in:
- Scientific Reports, 2017, p. 43047, doi. 10.1038/srep43047
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- Publication type:
- Article
Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies.
- Published in:
- AAPS Journal, 2019, v. 21, n. 5, p. N.PAG, doi. 10.1208/s12248-019-0344-8
- By:
- Publication type:
- Article
Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer.
- Published in:
- Therapeutic Advances in Medical Oncology, 2021, p. 1, doi. 10.1177/17588359211059896
- By:
- Publication type:
- Article
Newly developed dual topoisomerase inhibitor P8-D6 is highly active in ovarian cancer.
- Published in:
- Therapeutic Advances in Medical Oncology, 2021, p. 1, doi. 10.1177/17588359211059896
- By:
- Publication type:
- Article
Conditionally Immortalized Intestinal Epithelial Cells: A New Model for Studying Intestinal Epithelial Cell Turnover.
- Published in:
- Annals of the New York Academy of Sciences, 1998, v. 859, n. 1, p. 201, doi. 10.1111/j.1749-6632.1998.tb11128.x
- By:
- Publication type:
- Article
OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67192-6
- By:
- Publication type:
- Article
Short‐ and long‐term effects of body weight, calorie restriction and gastric bypass on CYP1A2, CYP2C19 and CYP2C9 activity.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 9, p. 4121, doi. 10.1111/bcp.15349
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- Publication type:
- Article
Cell‐type‐resolved proteomic analysis of the human liver.
- Published in:
- Liver International, 2020, v. 40, n. 7, p. 1770, doi. 10.1111/liv.14452
- By:
- Publication type:
- Article
Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range.
- Published in:
- European Journal of Clinical Pharmacology, 2022, v. 78, n. 8, p. 1289, doi. 10.1007/s00228-022-03336-9
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- Publication type:
- Article
CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil.
- Published in:
- Nature Communications, 2016, v. 7, n. 3, p. 11040, doi. 10.1038/ncomms11040
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- Publication type:
- Article
Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1142, doi. 10.1002/cpt.2558
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- Publication type:
- Article
Proteomics‐Informed Prediction of Rosuvastatin Plasma Profiles in Patients With a Wide Range of Body Weight.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 3, p. 762, doi. 10.1002/cpt.2056
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- Publication type:
- Article
Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 3, p. 525, doi. 10.1002/cpt.1537
- By:
- Publication type:
- Article
In silico and biological analyses of missense variants of the human biliary efflux transporter ABCC2: effects of novel rare missense variants.
- Published in:
- British Journal of Pharmacology, 2024, v. 181, n. 22, p. 4593, doi. 10.1111/bph.16508
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- Publication type:
- Article
Theoretical predictions of drug absorption in drug discovery and development.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2013, v. 40, n. 1, p. 117, doi. 10.1007/s10928-012-9293-x
- By:
- Publication type:
- Article
A miniaturized nebulization catheter for improved gene delivery to the mouse lung.
- Published in:
- Journal of Gene Medicine, 2005, v. 7, n. 9, p. 1215, doi. 10.1002/jgm.762
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- Publication type:
- Article
A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes.
- Published in:
- Archives of Toxicology, 2019, v. 93, n. 3, p. 819, doi. 10.1007/s00204-018-2375-9
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- Publication type:
- Article
182. Branched Chitosan Oligomers Enhance Gene Delivery In Vitro and after Lung Administration In Vivo.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S70, doi. 10.1016/j.ymthe.2006.08.206
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- Publication type:
- Article
Monitoring drug–target interactions through target engagement-mediated amplification on arrays and in situ.
- Published in:
- Nucleic Acids Research, 2022, v. 50, n. 22, p. e129, doi. 10.1093/nar/gkac842
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- Publication type:
- Article
Digoxin Pharmacokinetics in Patients with Obesity Before and After a Gastric Bypass or a Strict Diet Compared with Normal Weight Individuals.
- Published in:
- Clinical Pharmacokinetics, 2024, v. 63, n. 1, p. 109, doi. 10.1007/s40262-023-01320-9
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- Publication type:
- Article
Neither Gastric Bypass Surgery Nor Diet-Induced Weight-Loss Affect OATP1B1 Activity as Measured by Rosuvastatin Oral Clearance.
- Published in:
- Clinical Pharmacokinetics, 2023, v. 62, n. 5, p. 725, doi. 10.1007/s40262-023-01235-5
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- Publication type:
- Article
Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity.
- Published in:
- CTS: Clinical & Translational Science, 2022, v. 15, n. 11, p. 2685, doi. 10.1111/cts.13394
- By:
- Publication type:
- Article
Short‐ and long‐term effects of body weight loss following calorie restriction and gastric bypass on CYP3A‐activity – a non‐randomized three‐armed controlled trial.
- Published in:
- CTS: Clinical & Translational Science, 2022, v. 15, n. 1, p. 221, doi. 10.1111/cts.13142
- By:
- Publication type:
- Article
Illuminating the function of the orphan transporter, SLC22A10, in humans and other primates.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48569-7
- By:
- Publication type:
- Article
A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.
- Published in:
- Nature Protocols, 2017, v. 12, n. 7, p. 1387, doi. 10.1038/nprot.2017.041
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- Publication type:
- Article
Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-02025-2
- By:
- Publication type:
- Article
Preclinical Characterization of Acyl Sulfonimidamides: Potential Carboxylic Acid Bioisosteres with Tunable Properties.
- Published in:
- ChemMedChem, 2015, v. 10, n. 3, p. 455, doi. 10.1002/cmdc.201402497
- By:
- Publication type:
- Article
The choice of ultra‐low attachment plates impacts primary human and primary canine hepatocyte spheroid formation, phenotypes, and function.
- Published in:
- Biotechnology Journal, 2024, v. 19, n. 2, p. 1, doi. 10.1002/biot.202300587
- By:
- Publication type:
- Article
The choice of ultra‐low attachment plates impacts primary human and primary canine hepatocyte spheroid formation, phenotypes, and function.
- Published in:
- Biotechnology Journal, 2024, v. 19, n. 2, p. 1, doi. 10.1002/biot.202300587
- By:
- Publication type:
- Article
Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring.
- Published in:
- BMC Medicine, 2004, v. 2, p. 8, doi. 10.1186/1741-7015-2-8
- By:
- Publication type:
- Article
Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11).
- Published in:
- Toxicological Sciences, 2013, v. 136, n. 2, p. 328, doi. 10.1093/toxsci/kft197
- By:
- Publication type:
- Article
Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15111-4
- By:
- Publication type:
- Article
Cadmium Transport in a Model of Neonatal Intestinal Cells Correlates to MRP1 and Not DMT1 or FPN1.
- Published in:
- ISRN Toxicology, 2013, p. 1, doi. 10.1155/2013/892364
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- Publication type:
- Article
Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.
- Published in:
- Genome Medicine, 2018, v. 10, p. 1, doi. 10.1186/s13073-017-0511-4
- By:
- Publication type:
- Article
In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug-Drug Interactions.
- Published in:
- Pharmaceutical Research, 2012, v. 29, n. 2, p. 411, doi. 10.1007/s11095-011-0564-9
- By:
- Publication type:
- Article
Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs.
- Published in:
- Pharmaceutical Research, 2009, v. 26, n. 8, p. 1816, doi. 10.1007/s11095-009-9896-0
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- Publication type:
- Article