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- Title
Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review.
- Authors
Wang, Kaiyang; Zhang, Huhai; Yuan, Lie; Li, Xiaoli; Cai, Yongqing
- Abstract
Hyperoside is a flavonol glycoside mainly found in plants of the genera Hypericum and Crataegus, and also detected in many plant species such as Abelmoschus manihot, Ribes nigrum, Rosa rugosa, Agrostis stolonifera, Apocynum venetum and Nelumbo nucifera. This compound exhibits a multitude of biological functions including anti-inflammatory, antidepressant, antioxidative, vascular protective effects and neuroprotective effects, etc. This review summarizes the quantification, original plant, chemical structure and property, structure–activity relationship, pharmacologic effect, pharmacokinetics, toxicity and clinical application of hyperoside, which will be significant for the exploitation for new drug and full utilization of this compound.
- Subjects
CHEMICAL structure; EAST Indian lotus; STRUCTURE-activity relationships; DRUG utilization; CHEMICAL properties
- Publication
Journal of Inflammation Research, 2023, Vol 16, p4503
- ISSN
1178-7031
- Publication type
Article
- DOI
10.2147/JIR.S418222