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Activity of the Arabidopsis RD29A and RD29B promoter elements in soybean under water stress.
- Published in:
- Planta: An International Journal of Plant Biology, 2013, v. 237, n. 1, p. 55, doi. 10.1007/s00425-012-1740-9
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- Publication type:
- Article
Characterization of abiotic stress-responsive Arabidopsis thaliana RD29A and RD29B genes and evaluation of transgenes.
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- Planta: An International Journal of Plant Biology, 2011, v. 234, n. 1, p. 97, doi. 10.1007/s00425-011-1387-y
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- Publication type:
- Article
Modeling and Simulation to Inform Potential New Strategies for BACEi in Treatment of Alzheimers Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083036
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- Publication type:
- Article
Pooled Modeling of Disease Progression in Two BACE1 Inhibitor Verubecestat Trials in Prodromal to Moderate Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082993
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- Publication type:
- Article
Joint Exposure‐Response Analysis of PET Amyloid Plaque Data from the BACE1 Inhibitor Verubecestat and Amyloid mAbs Trials in Prodromal to Moderate Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.079519
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- Publication type:
- Article
P3‐040: VERUBECESTAT PHARMACOKINETIC AND EXPOSURE‐RESPONSE RESULTS FROM APECS, A PHASE 3 TRIAL IN PRODROMAL ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P941, doi. 10.1016/j.jalz.2019.06.3066
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- Publication type:
- Article
P2‐002: AN INTEGRATED MECHANISTIC AMYLOID PATHWAY MODEL INFORMED BY CLINICAL BIOMARKER DATA FROM VERUBECESTAT AND OTHER BACE INHIBITORS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P571, doi. 10.1016/j.jalz.2019.06.1224
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- Publication type:
- Article
P1‐044: VERUBECESTAT DISEASE PROGRESSION MODELING FROM APECS, A PHASE 3 TRIAL IN PRODROMAL ALZHEIMER'S DISEASE: NO DOSE‐ AND EXPOSURE‐DEPENDENCY IN CLINICAL ENDPOINTS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P249, doi. 10.1016/j.jalz.2019.06.069
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- Publication type:
- Article
P3‐031: THE CRITICAL PATH FOR ALZHEIMER'S DISEASE: HIPPOCAMPAL VOLUME AS AN ENRICHMENT BIOMARKER IN TRIALS OF PATIENTS WITH MILD COGNITIVE IMPAIRMENT.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1076, doi. 10.1016/j.jalz.2018.06.1386
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- Publication type:
- Article
P1‐038: VERUBECESTAT PHARMACOKINETIC AND EXPOSURE‐RESPONSE RESULTS FROM EPOCH: A PHASE 3 TRIAL IN MILD‐TO‐MODERATE ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P281, doi. 10.1016/j.jalz.2018.06.039
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- Publication type:
- Article
Within these hyperporous walls: An examination of a rebundled online learning model of higher education.
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- Australasian Journal of Educational Technology, 2020, v. 36, n. 5, p. 85, doi. 10.14742/ajet.6061
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- Publication type:
- Article
Maternal genetic diseases: potential concerns for mother and baby.
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- Human Genetics, 2020, v. 139, n. 9, p. 1173, doi. 10.1007/s00439-019-02086-6
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- Publication type:
- Article
Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance.
- Published in:
- Plant Journal, 2006, v. 47, n. 6, p. 851, doi. 10.1111/j.1365-313X.2006.02837.x
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- Publication type:
- Article
ArabidopsisAtSPL14, a plant-specific SBP-domain transcription factor, participates in plant development and sensitivity to fumonisin B1.
- Published in:
- Plant Journal, 2005, v. 41, n. 5, p. 744, doi. 10.1111/j.1365-313X.2005.02334.x
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- Publication type:
- Article
Reviews.
- Published in:
- Modern Law Review, 1999, v. 62, n. 3, p. 151, doi. 10.1111/1468-2230.t01-1-00198
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- Publication type:
- Article
Further analyses of the safety of verubecestat in the phase 3 EPOCH trial of mild-to-moderate Alzheimer's disease.
- Published in:
- Alzheimer's Research & Therapy, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13195-019-0520-1
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- Publication type:
- Article
ACUTE ADMINISTRATION OF A BACE INHIBITOR IN HEALTHY HUMANS RESULTS IN A SIGNIFICANT REDUCTION OF Aβ OLIGOMERS IN CEREBROSPINAL FLUID.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P574, doi. 10.1016/j.jalz.2017.07.192
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- Publication type:
- Article
SYSTEMS PHARMACOLOGY ANALYSIS OF THE Aβ OLIGOMER RESPONSE FOLLOWING BACE1 INHIBITION: EVIDENCE FOR SECOND-ORDER Aβ42 OLIGOMERIZATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P281, doi. 10.1016/j.jalz.2017.06.175
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- Publication type:
- Article
RESILIENCE MECHANISM OF THE AMYLOID PRECURSOR PROTEIN (APP) PATHWAY REVEALED BY SYSTEMS PHARMACOLOGY MODELING FOLLOWING β- AND GAMMA-SECRETASE INHIBITION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P630, doi. 10.1016/j.jalz.2017.06.715
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- Publication type:
- Article
THE COALITION AGAINST MAJOR DISEASES: TOWARD U.S. FDA QUALIFICATION OF HIPPOCAMPAL VOLUME AS A BIOMARKER FOR ENRICHMENT IN CLINICAL TRIALS FOR PRE-DEMENTIA STAGES OF ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1259, doi. 10.1016/j.jalz.2017.06.1878
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- Publication type:
- Article
IS THE PERIPHERAL SINK HYPOTHESIS PHYSIOLOGICALLY FEASIBLE? EVIDENCE FROM MODEL-BASED ASSESSMENT OF THE AMYLOID PATHWAY.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P443, doi. 10.1016/j.jalz.2016.06.855
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- Publication type:
- Article
EVIDENCE FROM MODEL-BASED ASSESSMENTS OF COMPOUNDS TESTED IN COMPLETED CLINICAL TRIALS INDICATES THAT THE AMYLOID HYPOTHESIS HAS NOT BEEN ADEQUATELY TESTED.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P609, doi. 10.1016/j.jalz.2016.06.1209
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- Publication type:
- Article
Abeta oligomers as a pharmacodynamic biomarker of secretase therapy in Alzheimer's disease?
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P325, doi. 10.1016/j.jalz.2015.07.469
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- Publication type:
- Article
Development and application of a mathematical model of modulation of cerebrospinal fluid Aβ40 after treatment with gamma- and beta-secretase inhibitors
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- 2012
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- Publication type:
- Abstract
An integrated mechanistic model to interrelate CSF Aβ40, Aβ42, sAPPβ and sAPPα response to β- and γ-secretase inhibitors in rhesus monkey
- Published in:
- 2012
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- Publication type:
- Abstract
Population pharmacokinetic modeling of the novel BACE inhibitor MK-8931 following single and multiple dose administration in healthy subjects
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- 2012
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- Publication type:
- Abstract
O4-03-02: The gamma secretase inhibitor MK-0752 acutely and significantly reduces CSF Abeta40 concentrations in humans
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- 2006
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- Publication type:
- Abstract
O4-03-02: The gamma secretase inhibitor MK-0752 acutely and significantly reduces CSF Abeta40 concentrations in humans
- Published in:
- 2006
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- Publication type:
- Abstract
The Uthando Project: Dolls for the Children of KwaZulu-Natal.
- Published in:
- Zero to Three, 2018, v. 38, n. 4, p. 79
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- Publication type:
- Article
Effect of Leading Questions on the Self-Monitoring-Memory Correlation.
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- Personality & Social Psychology Bulletin, 1987, v. 13, n. 4, p. 537, doi. 10.1177/0146167287134010
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- Publication type:
- Article
Physical Attractiveness and Skill at Detecting Deception.
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- Personality & Social Psychology Bulletin, 1987, v. 13, n. 2, p. 177
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- Publication type:
- Article
Affective Consequences of Variation in Behavior Perception.
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- Personality & Social Psychology Bulletin, 1984, v. 10, n. 2, p. 253
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- Publication type:
- Article
Attentional Determinants of Success at Detecting Deception and Truth.
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- Personality & Social Psychology Bulletin, 1982, v. 8, n. 2, p. 273, doi. 10.1177/0146167282082014
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- Publication type:
- Article
Ventilator Caregiver Education Through the Use of High-Fidelity Pediatric Simulators: A Pilot Study.
- Published in:
- Clinical Pediatrics, 2013, v. 52, n. 11, p. 1038, doi. 10.1177/0009922813505901
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- Publication type:
- Article
An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat.
- Published in:
- AAPS Journal, 2022, v. 24, n. 3, p. 1, doi. 10.1208/s12248-022-00683-4
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- Publication type:
- Article
A Model-Based Approach to Bridging Plasma and Dried Blood Spot Concentration Data for Phase 3 Verubecestat Trials.
- Published in:
- AAPS Journal, 2022, v. 24, n. 3, p. 1, doi. 10.1208/s12248-022-00682-5
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- Publication type:
- Article
An Integrated Strategy for Implementation of Dried Blood Spots in Clinical Development Programs.
- Published in:
- AAPS Journal, 2016, v. 18, n. 2, p. 519, doi. 10.1208/s12248-015-9860-3
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- Publication type:
- Article
A Semi-mechanistic Model for the Effects of a Novel Glucagon Receptor Antagonist on Glucagon and the Interaction Between Glucose, Glucagon, and Insulin Applied to Adaptive Phase II Design.
- Published in:
- AAPS Journal, 2014, v. 16, n. 6, p. 1259, doi. 10.1208/s12248-014-9648-x
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- Publication type:
- Article
Simultaneous Pharmacokinetic Model for Rolofylline and both M1-trans and M1-cis Metabolites.
- Published in:
- AAPS Journal, 2013, v. 15, n. 2, p. 498, doi. 10.1208/s12248-012-9443-5
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- Publication type:
- Article
Development of a Population Pharmacokinetic Model for Taranabant, a Cannibinoid-1 Receptor Inverse Agonist.
- Published in:
- AAPS Journal, 2010, v. 12, n. 4, p. 537, doi. 10.1208/s12248-010-9212-2
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- Publication type:
- Article
Model-Based Decision Making in Early Clinical Development: Minimizing the Impact of a Blood Pressure Adverse Event.
- Published in:
- AAPS Journal, 2009, v. 11, n. 1, p. 99, doi. 10.1208/s12248-009-9083-6
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- Publication type:
- Article
A Plant DJ-1 Homolog Is Essential for Arabidopsis thaliana Chloroplast Development.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023731
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- Publication type:
- Article
Steady-state pharmacokinetics of indinavir in cerebrospinal fluid and plasma among adults with human immunodeficiency virus type 1 infection<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2000, v. 68, n. 4, p. 367, doi. 10.1067/mcp.2000.109391
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- Publication type:
- Article
Evaluating the Comparative Effectiveness of Two Diets in Pediatric Inflammatory Bowel Disease: A Study Protocol for a Series of N-of-1 Trials.
- Published in:
- Healthcare (2227-9032), 2019, v. 7, n. 4, p. 129, doi. 10.3390/healthcare7040129
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- Publication type:
- Article
Interaction of the maize and Arabidopsis kinase interaction domains with a subset of receptor-like protein kinases: implications for transmembrane signaling in plants.
- Published in:
- Plant Journal, 1997, v. 12, n. 1, p. 83, doi. 10.1046/j.1365-313X.1997.12010083.x
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- Publication type:
- Article
Clinical and translational pharmacology of the cathepsin K inhibitor odanacatib studied for osteoporosis.
- Published in:
- British Journal of Clinical Pharmacology, 2019, v. 85, n. 6, p. 1072, doi. 10.1111/bcp.13869
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- Publication type:
- Article
Pharmacokinetic-pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2013, v. 76, n. 6, p. 917, doi. 10.1111/bcp.12131
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- Publication type:
- Article
Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics - results from single oral dose studies in healthy volunteers.
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- British Journal of Clinical Pharmacology, 2013, v. 75, n. 5, p. 1240, doi. 10.1111/j.1365-2125.2012.04471.x
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- Publication type:
- Article
Effect of raltegravir on estradiol and norgestimate plasma pharmacokinetics following oral contraceptive administration in healthy women.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 71, n. 4, p. 616, doi. 10.1111/j.1365-2125.2010.03885.x
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- Publication type:
- Article
Doubling: a model for international clinical partnerships.
- Published in:
- 2019
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- Publication type:
- journal article