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- Title
Copper-Catalyzed Three-Component Azidotrifluoromethylation/Difunctionalization of Alkenes.
- Authors
Mingbo Yang; Wenlu Wang; Yin Liu; Lijie Feng; Xuexia Ju
- Abstract
A novel three-component strategy for the azidotrifluoromethylation of alkenes has been presented here. The reaction proceeded smoothly under gentle temperature and gave the bifunctional olefins in high yields. Furthermore, 1,3-dipolar reactions between azide-containing products and phenylacetylene revealed great potential in molecular modification by using this method.
- Subjects
COPPER catalysts; TRIFLUOROMETHYL compounds synthesis; ALKENE synthesis; RING formation (Chemistry); LIPOPHILICITY; ETHYNYL benzene; AZIDES
- Publication
Chinese Journal of Chemistry, 2014, Vol 32, Issue 9, p833
- ISSN
1001-604X
- Publication type
Article
- DOI
10.1002/cjoc.201400167