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- Title
Venous thromboembolism in patients with head and neck cancer after surgery.
- Authors
Thai, Leo; McCarn, Kate; Stott, William; Watts, Tammara; Wax, Mark K.; Andersen, Peter E.; Gross, Neil D.
- Abstract
Background The purpose of this study was to report the incidence of venous thromboembolism (VTE) in patients with head and neck cancer after surgery. Methods This was a single-institution, retrospective cohort: 134 patients underwent resection and simultaneous microvascular reconstruction. The primary endpoint was identification of confirmed or suspicious VTE within 30 days of surgery. Results Two subjects (1.4%) with confirmed VTE (1 pulmonary embolism, 1 deep venous thrombosis) and 6 subjects (4.4%) with suspicious VTE (1 acute respiratory failure, 1 sudden cardiac arrest, and 4 cases of leg edema without imaging) were identified. The strongest predictors of possible VTE were prior VTE ( p = .004; odds ratio [OR], 25.11; 95% confidence interval [CI], 1.13-556.40), red cell transfusion ( p = .009; OR, 1.80; 95% CI, 1.16-2.80), high body mass index ( p = .015, OR, 1.29, 95% CI, 1.05-1.58), and older age ( p = .046; OR, 1.10; 95% CI, 1.00-1.19). Conclusion The incidence of VTE in patients with head and neck cancer after resection and microvascular reconstruction ranged from 1.4% to 5.8%. © 2012 Wiley Periodicals, Inc. Head Neck, 2013
- Subjects
VENOUS thrombosis; PULMONARY embolism; CANCER patients; SURGERY; SQUAMOUS cell carcinoma
- Publication
Head & Neck, 2013, Vol 35, Issue 1, p4
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.22920