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- Title
Chondromyxoid fibroma of the nasal septum: Case report and review of literature.
- Authors
McClurg, Stanley W.; Leon, Marino; Teknos, Theodoros N.; Iwenofu, O. Hans; Smith, Russell B.
- Abstract
Background. Chondromyxoid fibroma (CMF) is a rare bone tumor, accounting for less than 0.5% of all bone tumors, with a predilection for lower extremity bone metaphyses. Involvement of the head and neck is extremely rare, with only 3 cases reported in the nasal septum in world literature. Methods. This is a case report of a CMF in the nasal septum of a 49-year-old woman with a 6-month history of congestion. MRI showed a bilobed mass originating from the nasal septum. Histologic and immunoperoxidase staining as well as electron microscopic studies were performed. A literature review was performed. Results. The patient underwent a midface-degloving approach for surgical resection. The final pathology was prototypic of CMF. The patient was disease-free 16 months postoperatively. Conclusions. CMF is a rare, benign neoplasm occasionally occurring in the head and neck. Surgical resection is often curative. CMF must be differentiated from chondrosarcoma, given the substantial differences in treatment. © 2011 Wiley Periodicals, Inc. Head Neck, 2013
- Subjects
FIBROMAS; BONE tumors; NASAL tumors; ANTINEOPLASTIC agents; SURGICAL excision; ELECTRON microscopes; IMMUNOENZYME technique
- Publication
Head & Neck, 2013, Vol 35, Issue 1, pE1
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.21760