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- Title
Bone Strength Is Preserved Following Bariatric Surgery.
- Authors
Scibora, Lesley; Buchwald, Henry; Petit, Moira; Hughes, Julie; Ikramuddin, Sayeed
- Abstract
Background: There is an increasing concern that bariatric surgery results in excessive bone loss as demonstrated by studies that use areal bone mineral density (aBMD) outcomes by dual energy X-ray absorptiometry (DXA). Thus, we explored the effect of bariatric surgery on bone mechanical strength. Methods: Bone strength and body composition outcomes were measured in 21 adults (age 45.3 years; BMI 45.7 kg/m) at baseline (pre-surgery) and 3, 6, and 12 months post-surgery. Bone geometry, density and strength were assessed by peripheral quantitative computed tomography (pQCT) at the distal (4 %) sites of the radius and tibia and at the midshaft sites of the tibia (66 %) and radius (50 %). Participants were divided into tertiles (high, medium, and low) of percentage weight loss at 6 months post-surgery. Results: Participants in all three tertiles lost significant body weight by 6 months post-surgery (mean loss −5 to −30 %, all p < 0.05). At 6 months, all tertiles lost significant fat mass (−9 to −51 %, all p < 0.05), but only the high tertile lost significant fat-free mass (−8 %, p < 0.05). Despite a slight increase in tibia bone strength (SSIp) at 3 months (+1.1 %, p < 0.05), estimates of bone strength at the radius and tibia sites did not change at later post-surgical time points regardless of weight loss. Conclusions: Contrary to DXA-based aBMD outcomes in the current literature, these results suggest that bone strength was preserved up to 12 months following bariatric surgery. Future longer-term studies exploring bone strength and geometry are needed to confirm these findings.
- Subjects
MORBID obesity; BARIATRIC surgery; BONE density; COMPUTED tomography; HEALTH outcome assessment; WEIGHT loss; THERAPEUTICS
- Publication
Obesity Surgery, 2015, Vol 25, Issue 2, p263
- ISSN
0960-8923
- Publication type
Article
- DOI
10.1007/s11695-014-1341-8