We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Laparoscopic Greater Curvature Plication (LGCP) for Treatment of Morbid Obesity in a Series of 244 Patients.
- Authors
Fried, M.; Dolezalova, K.; Buchwald, J.; McGlennon, T.; Sramkova, P.; Ribaric, G.
- Abstract
Background: Laparoscopic greater curvature plication (LGCP) is a new metabolic/bariatric surgical procedure that requires no resection, bypass, or implantable device. We report LGCP outcomes in 244 morbidly obese patients. Methods: Between 2010 and 2011, patients underwent LGCP. Body mass index (BMI, kilogram per square meter) evolution, excess BMI loss (%EBMIL), excess weight loss (%EWL), complications, and type 2 diabetes mellitus (T2DM) changes were recorded. Repeated-measures analysis of variance (ANOVA) was used to assess weight change at 6, 12, and 18 months. Subgroup analyses were conducted to provide benchmark outcomes at 6 months. Logistic regression was used to identify characteristics predictive of suboptimal weight loss. Results: Mean baseline BMI (±SD) was 41.4 ± 5.5 (80.7 % women, mean age 46.1 ± 11.0 years, 68 [27.9 %] patients had T2DM). Mean operative time was 70.6 min; mean hospitalization, 36 h (24-72). Sixty-eight patients (27.9 %) experienced postoperative nausea and/or vomiting that was controlled within 36 h. There was no mortality. Major complication rate was 1.2 % ( n = 3). Repeated-measures ANOVA indicated significant weight loss across time points ( p < 0.001). At 6 months ( n = 105), BMI, %EBMIL, and %EWL were 36.1 ± 4.7, 34.8 ± 17.3, and 31.8 ± 15.9. Preoperative BMI was the only predictor of weight loss. Patients with BMI <40 lost more weight than those ≥40, although by 9 months, differences were no longer significant. In patients with preoperative BMI <40, 18-month %EWL approached 50 % and %EBMIL exceeded 50 %. At 6 months, 96.9 % of patients' T2DM was significantly improved/resolved. Conclusions: Over the short term, LGCP results in effective weight loss and significant T2DM reduction with a very low rate of complications.
- Subjects
LAPAROSCOPIC surgery; OBESITY treatment; SURGICAL excision; ARTIFICIAL implants; TYPE 2 diabetes; WEIGHT loss; HEALTH outcome assessment
- Publication
Obesity Surgery, 2012, Vol 22, Issue 8, p1298
- ISSN
0960-8923
- Publication type
Article
- DOI
10.1007/s11695-012-0684-2