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Association between liver X receptor alpha gene polymorphisms and risk of metabolic syndrome in French populations.
Published in:
2008
By:
- Legry V;
- Cottel D;
- Ferrières J;
- Chinetti G;
- Deroide T;
- Staels B;
- Amouyel P;
- Meirhaeghe A;
- Legry, V;
- Cottel, D;
- Ferrières, J;
- Chinetti, G;
- Deroide, T;
- Staels, B;
- Amouyel, P;
- Meirhaeghe, A
Publication type:
journal article
The effect of sensitisation to insulin with pioglitazone on fasting and postprandial lipid metabolism, lipoprotein modification by lipases, and lipid transfer activities in type 2 diabetic patients.
Published in:
Diabetologia, 2006, v. 49, n. 3, p. 527, doi. 10.1007/s00125-005-0092-4
By:
- Al Majali, K.;
- Cooper, M. B.;
- Staels, B.;
- Luc, G.;
- Taskinen, M.-R.;
- Betteridge, D. J.
Publication type:
Article
Variation in the PPARα gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects.
Published in:
Diabetologia, 2000, v. 43, n. 5, p. 673, doi. 10.1007/s001250051357
By:
- Flavell, D. M.;
- Torra, I. Pineda;
- Jamshidi, Y.;
- Evans, D.;
- Diamond, J. R.;
- Elkeles, R. S.;
- Bujac, S. R.;
- Miller, G.;
- Talmud, P. J.;
- Staels, B.;
- Humphries, S. E.
Publication type:
Article
Association of 1-deoxy-sphingolipids with steatosis but not steatohepatitis nor fibrosis in non-alcoholic fatty liver disease.
Published in:
Acta Diabetologica, 2021, v. 58, n. 3, p. 319, doi. 10.1007/s00592-020-01612-7
By:
- Weyler, J.;
- Verrijken, A.;
- Hornemann, T.;
- Vonghia, L.;
- Dirinck, E.;
- von Eckardstein, A.;
- Vanwolleghem, T.;
- Michielsen, P.;
- Peiffer, F.;
- Driessen, A.;
- Hubens, G.;
- Staels, B.;
- Francque, S.;
- Van Gaal, L.
Publication type:
Article
Inflammation, dyslipidaemia, diabetes and PPars: pharmacological interest of dual PPARalpha and PPARgamma agonists.
Published in:
2004
By:
- Gervois P;
- Fruchart JC;
- Staels B
Publication type:
Journal Article
Inflammation, dyslipidaemia, diabetes and PPARs: pharmacological interest of dual PPARα and PPARγ agonists.
Published in:
International Journal of Clinical Practice (Supplement), 2004, v. 58, p. 22, doi. 10.1111/j.1368-504X.2004.00376.x
By:
- Gervois, P.;
- Fruchart, J.-C.;
- Staels, B.
Publication type:
Article
Cell Culture Conditions Determine Apolipoprotein CIII Secretion and Regulation by Fibrates in Human Hepatoma HepG2 Cells.
Published in:
Cellular Physiology & Biochemistry (Karger AG), 1999, v. 9, n. 3, p. 139, doi. 10.1159/000016311
By:
- Clavey, V.;
- Copin, C.;
- Mariotte, M.C.;
- Baugé, E.;
- Chinetti, G.;
- Fruchart, J.;
- Fruchart, J.C.;
- Dallongeville, J.;
- Staels, B.
Publication type:
Article
The anti-obesity effect of rimonabant is associated with an improved serum lipid profile.
Published in:
Diabetes, Obesity & Metabolism, 2005, v. 7, n. 1, p. 65, doi. 10.1111/j.1463-1326.2004.00374.x
By:
- Poirier, B.;
- Bidouard, J.-P.;
- Cadrouvele, C.;
- Marniquet, X.;
- Staels, B.;
- O'Connor, S. E.;
- Janiak, P.;
- Herbert, J.-M.
Publication type:
Article
Downregulation of the tumour suppressor p16 contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype.
Published in:
Diabetologia, 2011, v. 54, n. 12, p. 3150, doi. 10.1007/s00125-011-2324-0
By:
- Fuentes, L.;
- Wouters, K.;
- Hannou, S.;
- Cudejko, C.;
- Rigamonti, E.;
- Mayi, T.;
- Derudas, B.;
- Pattou, F.;
- Chinetti-Gbaguidi, G.;
- Staels, B.;
- Paumelle, R.
Publication type:
Article
Skeletal muscle functions around the clock.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, p. 39, doi. 10.1111/dom.12517
By:
- Mayeuf-Louchart, A.;
- Staels, B.;
- Duez, H.
Publication type:
Article
Efficacy and safety of initial combination treatment with sitagliptin and pioglitazone-a factorial study.
Published in:
Diabetes, Obesity & Metabolism, 2014, v. 16, n. 3, p. 223, doi. 10.1111/dom.12194
By:
- Henry, R. R.;
- Staels, B.;
- Fonseca, V. A.;
- Chou, M. Z.;
- Teng, R.;
- Golm, G. T.;
- Langdon, R. B.;
- Kaufman, K. D.;
- Steinberg, H.;
- Goldstein, B. J.
Publication type:
Article
Peroxisome proliferator-activated receptors – from active regulators of macrophage biology to pharmacological targets in the treatment of cardiovascular disease.
Published in:
Journal of Internal Medicine, 2008, v. 263, n. 1, p. 28, doi. 10.1111/j.1365-2796.2007.01892.x
By:
- Bouhlel, M. A.;
- Staels, B.;
- Chinetti-Gbaguidi, G.
Publication type:
Article
No short-term effect of oral isotretinoin (13-cis retinoic acid) on lipoprotein(a) and HDL subclasses LP-A-I and LP-A-I:A-II in healthy volunteers.
Published in:
1999
By:
- Neele, D. M.;
- Buytenhek, R.;
- Staels, B.;
- Dallongeville, J.;
- Wallnöfer, A. E.;
- Kooistra, T.;
- Princen, H. M. G.;
- Wallnöfer, A E;
- Princen, H M
Publication type:
clinical trial
Temporal changes in bile acid levels and 12α-hydroxylation after Roux-en-Y gastric bypass surgery in type 2 diabetes.
Published in:
2015
By:
- Dutia, R;
- Embrey, M;
- O'Brien, S;
- Haeusler, R A;
- Agénor, K K;
- Homel, P;
- McGinty, J;
- Vincent, R P;
- Alaghband-Zadeh, J;
- Staels, B;
- le Roux, C W;
- Yu, J;
- Laferrère, B;
- O'Brien, C S
Publication type:
journal article
Temporal changes in bile acid levels and 12α-hydroxylation after Roux-en-Y gastric bypass surgery in type 2 diabetes.
Published in:
International Journal of Obesity, 2015, v. 39, n. 5, p. 806, doi. 10.1038/ijo.2015.1
By:
- Dutia, R;
- Embrey, M;
- O'Brien, S;
- Haeusler, R A;
- Agénor, K K;
- Homel, P;
- McGinty, J;
- Vincent, R P;
- Alaghband-Zadeh, J;
- Staels, B;
- le Roux, C W;
- Yu, J;
- Laferrère, B
Publication type:
Article
Bile acid sequestrants and the treatment of type 2 diabetes mellitus.
Published in:
2007
By:
- Staels B;
- Kuipers F
Publication type:
Journal Article
Nuclear transcription factors: new opportunities for lipid lowering.
Published in:
2000
By:
- Staels, B
Publication type:
journal article
The mitochondrion is the principal target for nutritional and pharmacological control of plasma triglyceride.
Published in:
Lipids, 1999, v. 34, p. S167, doi. 10.1007/BF02562277
By:
- Madsen, L.;
- Frøyland, L.;
- Kryvi, H.;
- Auwerx, J.;
- Staels, B.;
- Berge, R.
Publication type:
Article
Peroxisome Proliferator-Activated Receptor γ Induces the Expression of Tissue Factor Pathway Inhibitor-1 (TFPI-1) in Human Macrophages.
Published in:
PPAR Research, 2016, p. 1, doi. 10.1155/2016/2756781
By:
- Chinetti-Gbaguidi, G.;
- Copin, C.;
- Derudas, B.;
- Marx, N.;
- Eechkoute, J.;
- Staels, B.
Publication type:
Article
Profiling Serum Bile Acid Glucuronides in Humans: Gender Divergences, Genetic Determinants, and Response to Fenofibrate.
Published in:
Clinical Pharmacology & Therapeutics, 2013, v. 94, n. 4, p. 533, doi. 10.1038/clpt.2013.122
By:
- Trottier, J;
- Perreault, M;
- Rudkowska, I;
- Levy, C;
- Dallaire‐Theroux, A;
- Verreault, M;
- Caron, P;
- Staels, B;
- Vohl, M‐C;
- Straka, R J;
- Barbier, O
Publication type:
Article
Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan.
Published in:
2008
By:
- Clemenz M;
- Frost N;
- Schupp M;
- Caron S;
- Foryst-Ludwig A;
- Böhm C;
- Hartge M;
- Gust R;
- Staels B;
- Unger T;
- Kintscher U
Publication type:
Journal Article
PPARalpha agonists suppress osteopontin expression in macrophages and decrease plasma levels in patients with type 2 diabetes.
Published in:
2007
By:
- Nakamachi T;
- Nomiyama T;
- Gizard F;
- Heywood EB;
- Jones KL;
- Zhao Y;
- Fuentes L;
- Takebayashi K;
- Aso Y;
- Staels B;
- Inukai T;
- Bruemmer D
Publication type:
Journal Article
Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human {beta}-Cells and Adipose Tissue and Strong Association With Type 2 Diabetes.
Published in:
2006
By:
- Cauchi S;
- Meyre D;
- Dina C;
- Choquet H;
- Samson C;
- Gallina S;
- Balkau B;
- Charpentier G;
- Pattou F;
- Stetsyuk V;
- Scharfmann R;
- Staels B;
- Frühbeck G;
- Froguel P
Publication type:
Journal Article
Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.
Published in:
2006
By:
- Lalloyer F;
- Vandewalle B;
- Percevault F;
- Torpier G;
- Kerr-Conte J;
- Oosterveer M;
- Paumelle R;
- Fruchart J;
- Kuipers F;
- Pattou F;
- Fiévet C;
- Staels B
Publication type:
Journal Article
Therapeutic roles of peroxisome proliferator-activated receptor agonists.
Published in:
2005
By:
- Staels B;
- Fruchart J;
- Staels, Bart;
- Fruchart, Jean-Charles
Publication type:
journal article
PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.
Published in:
2001
By:
- Guerre-Millo, Michèle;
- Rouault, Christine;
- Poulain, Philippe;
- André, Jocelyne;
- Poitout, Vincent;
- Peters, Jeffrey M.;
- Gonzalez, Frank J.;
- Fruchart, Jean-Charles;
- Reach, Gérard;
- Staels, Bart;
- Guerre-Millo, M;
- Rouault, C;
- Poulain, P;
- André, J;
- Poitout, V;
- Peters, J M;
- Gonzalez, F J;
- Fruchart, J C;
- Reach, G;
- Staels, B
Publication type:
journal article
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients.
Published in:
1997
By:
- Auboeuf, Didier;
- Rieusset, Jennifer;
- Fajas, Lluis;
- Vallier, Paulette;
- Frering, Vincent;
- Riou, Jean Paul;
- Staels, Bart;
- Auwerx, Johan;
- Laville, Martine;
- Vidal, Hubert;
- Auboeuf, D;
- Rieusset, J;
- Fajas, L;
- Vallier, P;
- Frering, V;
- Riou, J P;
- Staels, B;
- Auwerx, J;
- Laville, M;
- Vidal, H
Publication type:
journal article
Generation and characterization of a humanized PPARδ mouse model.
Published in:
2011
By:
- Gross, B;
- Hennuyer, N;
- Bouchaert, E;
- Rommens, C;
- Grillot, D;
- Mezdour, H;
- Staels, B
Publication type:
journal article
The coronary artery disease-associated gene C6ORF105 is expressed in human macrophages under the transcriptional control of PPARγ.
Published in:
FEBS Letters, 2015, v. 589, n. 4, p. 461, doi. 10.1016/j.febslet.2015.01.002
By:
- Chinetti-Gbaguidi, G.;
- Copin, C.;
- Derudas, B.;
- Vanhoutte, J.;
- Zawadzki, C.;
- Jude, B.;
- Haulon, S.;
- Pattou, F.;
- Marx, N.;
- Staels, B.
Publication type:
Article
Topical ivermectin improves allergic skin inflammation.
Published in:
Allergy, 2017, v. 72, n. 8, p. 1212, doi. 10.1111/all.13118
By:
- Ventre, E.;
- Rozières, A.;
- Lenief, V.;
- Albert, F.;
- Rossio, P.;
- Laoubi, L.;
- Dombrowicz, D.;
- Staels, B.;
- Ulmann, L.;
- Julia, V.;
- Vial, E.;
- Jomard, A.;
- Hacini‐Rachinel, F.;
- Nicolas, J.‐F.;
- Vocanson, M.
Publication type:
Article
ATL>Peroxisome proliferator-activated receptor (PPAR) agonists decrease lipoprotein lipase secretion and glycated LDL uptake by human macrophages.
Published in:
FEBS Letters, 2002, v. 512, n. 1-3, p. 85, doi. 10.1016/S0014-5793(02)02223-8
By:
- Gbaguidi, F.G.;
- Chinetti, G.;
- Milosavljevic, D.;
- Teissier, E.;
- Chapman, J.;
- Olivecrona, G.;
- Fruchart, J.C.;
- Griglio, S.;
- Fruchart-Najib, J.;
- Staels, B.
Publication type:
Article
Effects of the new dual PPAR α/δ agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism.
Published in:
2011
By:
- Cariou B;
- Zaïr Y;
- Staels B;
- Bruckert E;
- Cariou, Bertrand;
- Zaïr, Yassine;
- Staels, Bart;
- Bruckert, Eric
Publication type:
journal article
Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration.
Published in:
2009
By:
- Staels B;
- Fonseca VA;
- Staels, Bart;
- Fonseca, Vivian A
Publication type:
journal article
85 Transcriptional regulation of cardiac fatty acid metabolism: redundancy of the ligand-activated nuclear hormone receptors PPARa and PPARb/d
Published in:
2004
By:
- Gilde, A.;
- Van der Lee, K.;
- Willemsen, P.;
- Chinetti, G.;
- Van der Leij, F.;
- Van der Vusse, G.;
- Staels, B.;
- Van Bilsen, M.
Publication type:
Abstract
A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population.
Published in:
Obesity (19307381), 2013, v. 21, n. 10, p. 2138, doi. 10.1002/oby.20366
By:
- Verrijken, A.;
- Beckers, S.;
- Francque, S.;
- Hilden, H.;
- Caron, S.;
- Zegers, D.;
- Ruppert, M.;
- Hubens, G.;
- Marck, E.;
- Michielsen, P.;
- Staels, B.;
- Taskinen, M.‐R.;
- Hul, W.;
- Gaal, L.
Publication type:
Article
Association between liver X receptor α gene polymorphisms and risk of metabolic syndrome in French populations.
Published in:
International Journal of Obesity, 2008, v. 32, n. 3, p. 421, doi. 10.1038/sj.ijo.0803705
By:
- Legry, V.;
- Cottel, D.;
- Ferrières, J.;
- Chinetti, G.;
- Deroide, T.;
- Staels, B.;
- Amouyel, P.;
- Meirhaeghe, A.
Publication type:
Article
Bile acid metabolism and the pathogenesis of type 2 diabetes.
Published in:
2011
By:
- Prawitt J;
- Caron S;
- Staels B;
- Prawitt, Janne;
- Caron, Sandrine;
- Staels, Bart
Publication type:
journal article
Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity.
Published in:
2011
By:
- Favre D;
- Le Gouill E;
- Fahmi D;
- Verdumo C;
- Chinetti-Gbaguidi G;
- Staels B;
- Caiazzo R;
- Pattou F;
- Lê KA;
- Tappy L;
- Regazzi R;
- Giusti V;
- Vollenweider P;
- Waeber G;
- Abderrahmani A;
- Favre, Dimitri;
- Le Gouill, Eric;
- Fahmi, Denis;
- Verdumo, Chantal;
- Chinetti-Gbaguidi, Giulia
Publication type:
journal article
The natural protective mechanism against hyperglycemia in vascular endothelial cells: roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor delta.
Published in:
2010
By:
- Riahi Y;
- Sin-Malia Y;
- Cohen G;
- Alpert E;
- Gruzman A;
- Eckel J;
- Staels B;
- Guichardant M;
- Sasson S;
- Riahi, Yael;
- Sin-Malia, Yoav;
- Cohen, Guy;
- Alpert, Evgenia;
- Gruzman, Arie;
- Eckel, Juergen;
- Staels, Bart;
- Guichardant, Michel;
- Sasson, Shlomo
Publication type:
journal article

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