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- Title
Alkalis and Skin.
- Authors
Greenwood, John E.; Jin Lin Tan; Justin Choong Tzen Ming; Abell, Andrew D.; Tan, Jin Lin; Ming, Justin Choong Tzen
- Abstract
The aim of this editorial is to provide an overview of the chemical interactions occurring in the skin of our patients on contact with alkaline agents. Strongly basic alkali is highly aggressive and will readily hydrolyze (or cleave) key biological molecules such as lipids and proteins. This phenomenon is known as saponification in the case of lipids and liquefactive denaturation for peptides and proteins. A short section on current first-aid concepts is included. A better understanding of the basic science behind alkali burns will make us better teachers and provide an insight into the urgency needed in treating these common and dangerous chemical injuries.
- Publication
Journal of Burn Care & Research, 2016, Vol 37, Issue 2, p135
- ISSN
1559-047X
- Publication type
journal article
- DOI
10.1097/BCR.0000000000000222