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- Title
Recent advances in the electrochemistry and spectroelectrochemistry of membrane proteins.
- Authors
Melin, Frederic; Hellwig, Petra
- Abstract
Integral membrane proteins are encountered in fundamental natural processes, such as photosynthe-sis and respiration. The relation between the structure of the proteins and their function and dynamics are still not clear in most cases. Once fully understood, these pro-cesses could ultimately help researchers to develop alter-native methods for producing energy, either from light or biomass. They could also lead to more efficient anti-biotics, which would selectively inhibit a specific mem-brane protein of pathogenic bacteria. Since the chemical reactions involved in both photosynthesis and respiration are redox reactions, electrochemical methods can play a considerable role in uncovering their mechanisms. The electrochemical characterization of membrane proteins is, however, quite challenging. An overview on the tech-niques used for the characterization of membrane pro-teins, including classical approaches such as voltammetry and spectroelectrochemistry, and recent developments, such as their combination with surface-enhanced tech-niques is given.
- Subjects
BIOELECTROCHEMISTRY; MEMBRANE proteins; BIOENERGETICS; VOLTAMMETRY; BIOMASS; PHOTOSYNTHESIS; PATHOGENIC bacteria
- Publication
Biological Chemistry, 2013, Vol 394, Issue 5, p593
- ISSN
1431-6730
- Publication type
Article
- DOI
10.1515/hsz-2012-0344