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- Title
An Ultrasensitive DNA Sensor for Hg<sup>2+</sup> Assay Based on Electrodeposited Au/Carbon Nanofibers‐chitosan and Reduced Graphene Oxide.
- Authors
Lv, Zeping; Zhang, Mingli; Jin, Huali; Wei, Min
- Abstract
An ultrasensitive electrochemical DNA sensor was designed for Hg2+ assay using cooperative signal amplification effect of electrodeposited Au/carbon nanofibers‐chitosan (DpAu/CNFs‐CS) and reduced graphene oxide (RGO). CNFs‐CS was prepared to modify gold electrode (AuE). Then, Au was electrodeposited on CNFs‐CS/AuE to form DpAu/CNFs‐CS/AuE for the first signal amplification. With TH as signal probe and ssDNA as recognition component, RGO/ssDNA and RGO/TH interaction were used for the second signal amplification. The prepared sensor had wider linear range of 0.0001–460 nM and lower detection limit of 5.7×10−5 nM, high selectivity, and performed well in Hg2+ assay of tap water.
- Subjects
GRAPHENE oxide; ELECTROCHEMICAL sensors; DNA; GOLD electrodes; SINGLE-stranded DNA; CARBON nanofibers
- Publication
Electroanalysis, 2023, Vol 35, Issue 2, p1
- ISSN
1040-0397
- Publication type
Article
- DOI
10.1002/elan.202200152