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- Title
Steroidal Alkaloids from the Roots and Rhizomes of Vertrum nigrum L.
- Authors
Yue Cong; William Jia; Jing Chen; Shuang Song; Jin-Hui Wang; Yu-Hui Yang
- Abstract
Two new steroidal alkaloids, neoverapatuline (1) and (1β,3α,5β)-1,3-dihydroxyjervanin-12-en-11-one (2), together with the four known compounds, veratramine (3), rubijervine (4), veratrosine (5), and veratroylzygadenine (6), were isolated from the roots and rhizomes of Veratrum nigrum L. Their structures were established through combined analyses of physicochemical properties and spectroscopic evidence. All compounds 1–6 were tested for their cytotoxicities in vitro against the human glioma cell line SF188.
- Subjects
ALKALOIDS; MICROBIAL metabolites; FALSE hellebores; LILIACEAE
- Publication
Helvetica Chimica Acta, 2007, Vol 90, Issue 5, p1038
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.200790087