We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Caractéristiques des enfants atopiques développant une surinfection herpétique : syndrome de Kaposi-Juliesburg À propos de 10 cas.
- Authors
Kassel, Jihad; Baybay, Hanane; Jroundi, Chaymae; Soughi, Meryem; Elloudi, Sara; Douhi, Zakia; Mernissi, Fz
- Abstract
Background: Atopic dermatitis (AD) is a chronic and recurrent inflammatory dermatosis, It results from the interaction of genetic and environmental factors that lead to defects in the skin barrier and an inappropriate immunological response. Kaposi varicelliform eruption or eczema herpeticum is a viral infection, caused mainly by reactivation of HSV-1 that affects about 3% of patients with AD. The objective of our study is to identify the characteristics of our atopic patients who developed eczema herpeticum. Material and methods: We conducted a prospective study that collected all cases of Kaposi’s varicelliform eruption in our patients with atopic dermatitis over a period of 2 years. Results: 10 children, with an average age of 26 months and a sex ratio of 0.6. Personal or family history of atopy was reported in 7 patients. As for disease severity, 2 patients had severe AD and the rest had moderate AD. Clinically, an acute presentation of the eruption was found in all our patients with an average of 3 days. A fever was reported in 5 patients associated with irritability. Typical vesicles were found in 8 children, with a herpetiform grouping in 5 children, erosions and crusts were reported in 7 children. All our patients had xerosis, erythematous squamous eczematous plaques were reported in 6 patients. Concerning the location of the lesions, facial involvement was observed in 7 children. Cytodiagnosis of Tzanck was performed in 3 children. We reported the application of a traditional treatment a few days before the onset of the herpetic superinfection in 8 children. We also found associated bacterial superinfection in 6 children. All our patients were hospitalized and received an intravenous treatment. Conclusion: early identification of patients at risk of viral complications would be important to develop effective prevention strategies and to develop new therapeutic options targeting components of the immune system.
- Subjects
ATOPIC dermatitis; IMMUNOLOGY; KAPOSI varicelliform eruption; ECZEMA; SKIN inflammation; XEROPHTHALMIA
- Publication
Cahiers Santé - Médecine Thérapeutique, 2023, Vol 32, Issue 1, p43
- ISSN
2780-8858
- Publication type
Article
- DOI
10.1684/sanmt.2023.174