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- Title
Reação de Meti I ação da Lisina Metiltransferase e Silenciamento de Genes no Rastreio do Desenvolvimento do Câncer.
- Authors
Tavares Amorim, Murilo; Ribeiro Cruz, Ana Cecília; Lopes Ferreira, Jardel Fábio; de Jesus Sizo Oliveira, Deborah; de Melo, Célio Amoêdo; Carvalho Pinto, Caroline; Franco Neto, Walter Félix; Moraes Holanda, Gustavo
- Abstract
Objective: To investigate the different roles of lysine methyltransferase H3K9 methylation in gene silencing associated with screening for cancer development. Methods: This is a literature review, based on the presentation and synthesis of selected studies on the role of lysine methyltransferase H3K9 protein methylation and gene silencing. The databases used in the material screening were the search platforms: Nature, Medical Literature Analysis and Retrieval System Online (Medline), Scientific Electronic Library Online (SciELO) and Science Direct. Results: 32 studies related to the proposed theme were identified. After screening the records obtained by searching the databases, 6 works that portrayed the study proposal were obtained as the final product of the articles included in the review. Conclusion: An updated and specific overview of the cellular and molecular effects underlying the activity of H3K9 on cancer development and progression is presented.
- Publication
Saúde Coletiva, 2021, Vol 11, Issue 70, p8774
- ISSN
1806-3365
- Publication type
Article
- DOI
10.36489/saudecoletiva.2021v11i70p8774-8789