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Innovations, challenges, and minimal information for standardization of humanized mice.
Published in:
EMBO Molecular Medicine, 2020, v. 12, n. 7, p. 1, doi. 10.15252/emmm.201708662
By:
- Stripecke, Renata;
- Münz, Christian;
- Schuringa, Jan Jacob;
- Bissig, Karl‐Dimiter;
- Soper, Brian;
- Meeham, Terrence;
- Yao, Li‐Chin;
- Di Santo, James P;
- Brehm, Michael;
- Rodriguez, Estefania;
- Wege, Anja Kathrin;
- Bonnet, Dominique;
- Guionaud, Silvia;
- Howard, Kristina E;
- Kitchen, Scott;
- Klein, Florian;
- Saeb‐Parsy, Kourosh;
- Sam, Johannes;
- Sharma, Amar Deep;
- Trumpp, Andreas
Publication type:
Article
Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73.
Published in:
Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02721-x
By:
- Jarvis, Lorna B.;
- Rainbow, Daniel B.;
- Coppard, Valerie;
- Howlett, Sarah K.;
- Georgieva, Zoya;
- Davies, Jessica L.;
- Mullay, Harpreet Kaur;
- Hester, Joanna;
- Ashmore, Tom;
- Van Den Bosch, Aletta;
- Grist, James T.;
- Coles, Alasdair J.;
- Mousa, Hani S.;
- Pluchino, Stefano;
- Mahbubani, Krishnaa T.;
- Griffin, Julian L.;
- Saeb-Parsy, Kourosh;
- Issa, Fadi;
- Peruzzotti-Jametti, Luca;
- Wicker, Linda S.
Publication type:
Article
Immunological considerations and challenges for regenerative cellular therapies.
Published in:
Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02237-4
By:
- Petrus-Reurer, Sandra;
- Romano, Marco;
- Howlett, Sarah;
- Jones, Joanne Louise;
- Lombardi, Giovanna;
- Saeb-Parsy, Kourosh
Publication type:
Article
Opportunities and Challenges in Using Social Media in Organ Donation.
Published in:
2020
By:
- Ayorinde, John O. O.;
- Saeb-Parsy, Kourosh;
- Hossain, Ayaz
Publication type:
journal article
RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27923-z
By:
- Belenguer, Germán;
- Mastrogiovanni, Gianmarco;
- Pacini, Clare;
- Hall, Zoe;
- Dowbaj, Anna M.;
- Arnes-Benito, Robert;
- Sljukic, Aleksandra;
- Prior, Nicole;
- Kakava, Sofia;
- Bradshaw, Charles R.;
- Davies, Susan;
- Vacca, Michele;
- Saeb-Parsy, Kourosh;
- Koo, Bon-Kyoung;
- Huch, Meritxell
Publication type:
Article
Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.
Published in:
Nature Biotechnology, 2015, v. 33, n. 8, p. 845, doi. 10.1038/nbt.3275
By:
- Sampaziotis, Fotios;
- Cardoso de Brito, Miguel;
- Madrigal, Pedro;
- Bertero, Alessandro;
- Saeb-Parsy, Kourosh;
- Soares, Filipa A C;
- Schrumpf, Elisabeth;
- Melum, Espen;
- Karlsen, Tom H;
- Bradley, J Andrew;
- Gelson, William T H;
- Davies, Susan;
- Baker, Alastair;
- Kaser, Arthur;
- Alexander, Graeme J;
- Hannan, Nicholas R F;
- Vallier, Ludovic
Publication type:
Article
Mesothelioma with non-pleural malignancy: a red herring or just an uncommon pairing?
Published in:
2006
By:
- Drain, Andrew J.;
- Saeb-Parsy, Kourosh;
- Shah, Amit K.;
- Rassl, D.;
- Ritchie, Andrew J.
Publication type:
Case Study
Modeling human tumor-immune environments in vivo for the preclinical assessment of immunotherapies.
Published in:
Cancer Immunology, Immunotherapy, 2021, v. 70, n. 10, p. 2737, doi. 10.1007/s00262-021-02897-5
By:
- Bareham, Bethany;
- Georgakopoulos, Nikitas;
- Matas-Céspedes, Alba;
- Curran, Michelle;
- Saeb-Parsy, Kourosh
Publication type:
Article
Generation of functional hepatocytes by forward programming with nuclear receptors.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.71591
By:
- Tomaz, Rute A.;
- Zacharis, Ekaterini D.;
- Bachinger, Fabian;
- Wurmser, Annabelle;
- Yamamoto, Daniel;
- Petrus-Reurer, Sandra;
- Morell, Carola M.;
- Dziedzicka, Dominika;
- Wesley, Brandon T.;
- Geti, Imbisaat;
- Segeritz, Charis-Patricia;
- de Brito, Miguel C.;
- Chhatriwala, Mariya;
- Ortmann, Daniel;
- Saeb-Parsy, Kourosh;
- Vallier, Ludovic
Publication type:
Article
An analysis of the survival outcomes of simultaneous pancreas and kidney transplantation compared to live donor kidney transplantation in patients with type 1 diabetes: a UK Transplant Registry study.
Published in:
Transplant International, 2017, v. 30, n. 9, p. 884, doi. 10.1111/tri.12957
By:
- Barlow, Adam D.;
- Saeb-Parsy, Kourosh;
- Watson, Christopher J. E.
Publication type:
Article
A single-centre experience of Roux-en-Y enteric drainage for pancreas transplantation.
Published in:
Transplant International, 2017, v. 30, n. 4, p. 410, doi. 10.1111/tri.12920
By:
- Amin, Irum;
- Butler, Andrew J.;
- Defries, Gail;
- Russell, Neil K.;
- Harper, Simon J. F.;
- Jah, Asif;
- Saeb-Parsy, Kourosh;
- Pettigrew, Gavin J.;
- Watson, Christopher J. E.
Publication type:
Article
Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves.
Published in:
Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01299-0
By:
- Gupta, Isha;
- Cassará, Antonino M.;
- Tarotin, Ilya;
- Donega, Matteo;
- Miranda, Jason A.;
- Sokal, David M.;
- Ouchouche, Sebastien;
- Dopson, Wesley;
- Matteucci, Paul;
- Neufeld, Esra;
- Schiefer, Matthew A.;
- Rowles, Alison;
- McGill, Paul;
- Perkins, Justin;
- Dolezalova, Nikola;
- Saeb-Parsy, Kourosh;
- Kuster, Niels;
- Yazicioglu, Refet Firat;
- Witherington, Jason;
- Chew, Daniel J.
Publication type:
Article
Risk for arterial thrombosis after liver transplantation with hepatic artery reconstruction.
Published in:
BJS Open, 2022, v. 6, n. 1, p. 1, doi. 10.1093/bjsopen/zrab146
By:
- Ghazaly, Mohamed;
- Sethi, Pulkit;
- Kathirvel, Manikandan;
- Tiwari, Navneet A.;
- Thillai, Manoj;
- Gaurav, Rohit;
- Surendrakumar, Veena;
- Ayorinde, John O. O.;
- Allison, Michael;
- Upponi, Sara;
- Watson, Christopher J.;
- Praseedom, Raaj K.;
- Gibbs, Paul;
- Saeb-Parsy, Kourosh
Publication type:
Article
Mechanism of succinate efflux upon reperfusion of the ischaemic heart.
Published in:
Cardiovascular Research, 2021, v. 117, n. 4, p. 1188, doi. 10.1093/cvr/cvaa148
By:
- Prag, Hiran A;
- Gruszczyk, Anja V;
- Huang, Margaret M;
- Beach, Timothy E;
- Young, Timothy;
- Tronci, Laura;
- Nikitopoulou, Efterpi;
- Mulvey, John F;
- Ascione, Raimondo;
- Hadjihambi, Anna;
- Shattock, Michael J;
- Pellerin, Luc;
- Saeb-Parsy, Kourosh;
- Frezza, Christian;
- James, Andrew M;
- Krieg, Thomas;
- Murphy, Michael P;
- Aksentijević, Dunja
Publication type:
Article
Recent Advancements and Applications of Human Immune System Mice in Preclinical Immuno-Oncology.
Published in:
Toxicologic Pathology, 2020, v. 48, n. 2, p. 302, doi. 10.1177/0192623319886304
By:
- Curran, Michelle;
- Mairesse, Maelle;
- Matas-Céspedes, Alba;
- Bareham, Bethany;
- Pellegrini, Giovanni;
- Liaunardy, Ardi;
- Powell, Edward;
- Sargeant, Rebecca;
- Cuomo, Emanuela;
- Stebbings, Richard;
- Betts, Catherine J.;
- Saeb-Parsy, Kourosh
Publication type:
Article
Two subsets of human marginal zone B cells resolved by global analysis of lymphoid tissues and blood.
Published in:
Science Immunology, 2022, v. 7, n. 69, p. 1, doi. 10.1126/sciimmunol.abm9060
By:
- Siu, Jacqueline H. Y.;
- Pitcher, Michael J.;
- Tull, Thomas J.;
- Velounias, Rebekah L.;
- Guesdon, William;
- Montorsi, Lucia;
- Mahbubani, Krishnaa T.;
- Ellis, Richard;
- Dhami, Pawan;
- Todd, Katrina;
- Kadolsky, Ulrich D.;
- Kleeman, Michelle;
- D’Cruz, David P.;
- Saeb-Parsy, Kourosh;
- Bemark, Mats;
- Pettigrew, Gavin J.;
- Spencer, Jo
Publication type:
Article
Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys.
Published in:
Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aam6764
By:
- Tietjen, Gregory T.;
- Hosgood, Sarah A.;
- DiRito, Jenna;
- Jiajia Cui;
- Deep, Deeksha;
- Song, Eric;
- Kraehling, Jan R.;
- Piotrowski-Daspit, Alexandra S.;
- Kirkiles-Smith, Nancy C.;
- Al-Lamki, Rafia;
- Thiru, Sathia;
- Bradley, J. Andrew;
- Saeb-Parsy, Kourosh;
- Bradley, John R.;
- Nicholson, Michael L.;
- Saltzman, W. Mark;
- Pober, Jordan S.
Publication type:
Article
The cholinergic anti-inflammatory pathway inhibits inflammation without lymphocyte relay.
Published in:
Frontiers in Neuroscience, 2023, p. 1, doi. 10.3389/fnins.2023.1125492
By:
- Simon, Thomas;
- Kirk, Joseph;
- Dolezalova, Nikola;
- Guyot, Mélanie;
- Panzolini, Clara;
- Bondue, Alexandre;
- Lavergne, Julien;
- Hugues, Sandrine;
- Hypolite, Nicolas;
- Saeb-Parsy, Kourosh;
- Perkins, Justin;
- Macia, Eric;
- Sridhar, Arun;
- Vervoordeldonk, Margriet J.;
- Glaichenhaus, Nicolas;
- Donegá, Matteo;
- Blancou, Philippe
Publication type:
Article
Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids.
Published in:
BMC Developmental Biology, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12861-020-0209-5
By:
- Georgakopoulos, Nikitas;
- Prior, Nicole;
- Angres, Brigitte;
- Mastrogiovanni, Gianmarco;
- Cagan, Alex;
- Harrison, Daisy;
- Hindley, Christopher J.;
- Arnes-Benito, Robert;
- Liau, Siong-Seng;
- Curd, Abbie;
- Ivory, Natasha;
- Simons, Benjamin D.;
- Martincorena, Inigo;
- Wurst, Helmut;
- Saeb-Parsy, Kourosh;
- Huch, Meritxell
Publication type:
Article
Metabolomic Profiling in Acute ST-Segment-Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia-Reperfusion Injury.
Published in:
2018
By:
- Kohlhauer, Matthias;
- Dawkins, Sam;
- Costa, Ana S. H.;
- Lee, Regent;
- Young, Timothy;
- Pell, Victoria R.;
- Choudhury, Robin P.;
- Banning, Adrian P.;
- Kharbanda, Rajesh K.;
- Saeb-Parsy, Kourosh;
- Murphy, Michael P.;
- Frezza, Christian;
- Krieg, Thomas;
- Channon, Keith M.;
- Oxford Acute Myocardial Infarction (OxAMI) Study
Publication type:
journal article
Bioengineering solutions for ureteric disorders: clinical need, challenges and opportunities.
Published in:
BJU International, 2022, v. 130, n. 4, p. 408, doi. 10.1111/bju.15741
By:
- Kapetanos, Konstantinos;
- Light, Alexander;
- Thakare, Niyukta;
- Mahbubani, Krishnaa;
- Saeb‐Parsy, Kasra;
- Saeb‐Parsy, Kourosh
Publication type:
Article
Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury.
Published in:
Pediatric Nephrology, 2019, v. 34, n. 7, p. 1167, doi. 10.1007/s00467-018-3984-5
By:
- Martin, Jack L.;
- Gruszczyk, Anja V.;
- Beach, Timothy E.;
- Murphy, Michael P.;
- Saeb-Parsy, Kourosh
Publication type:
Article
Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo.
Published in:
Cardiovascular Drugs & Therapy, 2022, v. 36, n. 1, p. 1, doi. 10.1007/s10557-020-07033-6
By:
- Prag, Hiran A.;
- Pala, Laura;
- Kula-Alwar, Duvaraka;
- Mulvey, John F.;
- Luping, Du;
- Beach, Timothy E.;
- Booty, Lee M.;
- Hall, Andrew R.;
- Logan, Angela;
- Sauchanka, Volha;
- Caldwell, Stuart T.;
- Robb, Ellen L.;
- James, Andrew M.;
- Xu, Zhelong;
- Saeb-Parsy, Kourosh;
- Hartley, Richard C.;
- Murphy, Michael P.;
- Krieg, Thomas
Publication type:
Article
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Published in:
Nature, 2014, v. 515, n. 7527, p. 431, doi. 10.1038/nature13909
By:
- Chouchani, Edward T.;
- Eaton, Simon;
- Davidson, Sean M.;
- Saeb-Parsy, Kourosh;
- Pell, Victoria R.;
- Hu, Chou-Hui;
- Krieg, Thomas;
- Gaude, Edoardo;
- Costa, Ana S. H.;
- Frezza, Christian;
- Aksentijević, Dunja;
- Shattock, Michael J.;
- Sundier, Stephanie Y.;
- Duchen, Michael R.;
- Robb, Ellen L.;
- Logan, Angela;
- Smith, Anthony C.;
- Eyassu, Filmon;
- Dare, Anna J.;
- James, Andrew M.
Publication type:
Article
Use of human splenocytes in an innovative humanised mouse model for prediction of immunotherapy‐induced cytokine release syndrome.
Published in:
Clinical & Translational Immunology, 2020, v. 9, n. 11, p. 1, doi. 10.1002/cti2.1202
By:
- Matas‐Céspedes, Alba;
- Brown, Lee;
- Mahbubani, Krishnaa T;
- Bareham, Bethany;
- Higgins, Jackie;
- Curran, Michelle;
- de Haan, Lolke;
- Lapointe, Jean‐Martin;
- Stebbings, Richard;
- Saeb‐Parsy, Kourosh
Publication type:
Article
Talc Seromadesis: A Novel Technique for the Treatment of Chronic Seromas Following Breast Surgery.
Published in:
2006
By:
- Saeb-Parsy, Kourosh;
- Athanassoglou, Vassilis;
- Benson, John R.
Publication type:
Letter
Development of an objective, standardized tool for surgical assessment of deceased donor kidneys: The Cambridge Kidney Assessment Tool.
Published in:
Clinical Transplantation, 2020, v. 34, n. 2, p. N.PAG, doi. 10.1111/ctr.13782
By:
- Ayorinde, John O. O.;
- Hamed, Mazin;
- Goh, Mingzheng Aaron;
- Summers, Dominic M.;
- Dare, Anna;
- Chen, Yining;
- Saeb‐Parsy, Kourosh
Publication type:
Article
Ureteric complications in recipients of kidneys from donation after circulatory death donors.
Published in:
Clinical Transplantation, 2017, v. 31, n. 4, p. n/a, doi. 10.1111/ctr.12912
By:
- Mah, Trina‐Jo;
- Mallon, Dermot H.;
- Brewster, Oliver;
- Saeb‐Parsy, Kourosh;
- Butler, Andrew J.;
- Bradley, J. Andrew;
- Kosmoliaptsis, Vasilis
Publication type:
Article
The discard of deceased donor kidneys in the UK.
Published in:
Clinical Transplantation, 2014, v. 28, n. 3, p. 345, doi. 10.1111/ctr.12319
By:
- Callaghan, Chris J.;
- Harper, Simon J.F.;
- Saeb‐Parsy, Kourosh;
- Hudson, Alex;
- Gibbs, Paul;
- Watson, Christopher J.E.;
- Praseedom, Raaj K.;
- Butler, Andrew J.;
- Pettigrew, Gavin J.;
- Bradley, J. Andrew
Publication type:
Article
FlowAtlas: an interactive tool for high-dimensional immunophenotyping analysis bridging FlowJo with computational tools in Julia.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1425488
By:
- Coppard, Valerie;
- Szep, Grisha;
- Georgieva, Zoya;
- Howlett, Sarah K.;
- Jarvis, Lorna B.;
- Rainbow, Daniel B.;
- Suchanek, Ondrej;
- Needham, Edward J.;
- Mousa, Hani S.;
- Menon, David K.;
- Feyertag, Felix;
- Mahbubani, Krishnaa T.;
- Saeb-Parsy, Kourosh;
- Jones, Joanne L.
Publication type:
Article
Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue.
Published in:
Nature Protocols, 2019, v. 14, n. 6, p. 1884, doi. 10.1038/s41596-019-0168-0
By:
- Tysoe, Olivia C.;
- Justin, Alexander W.;
- Brevini, Teresa;
- Chen, Si Emma;
- Mahbubani, Krishnaa T.;
- Frank, Anna K.;
- Zedira, Hajer;
- Melum, Espen;
- Saeb-Parsy, Kourosh;
- Markaki, Athina E.;
- Vallier, Ludovic;
- Sampaziotis, Fotios
Publication type:
Article

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