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- Title
First Analog of Pyrimidine Nucleosides with Two D-Ribofuranose Residues.
- Authors
Sharipova, R. R.; Saifina, L. F.; Belenok, M. G.; Semenov, V. E.; Kataev, V. E.
- Abstract
The reaction of 1,3-bis(pent-4-yn-1-yl)-6-methyluracil with 2,3,5-tri-O-acetyl-β-D-ribofuranosyl azide gave 1,3-bis{3-[1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1H-1,2,3-triazol-4-yl]propyl}-6-methyluracil which was deprotected by treatment with a solution of sodium methoxide in methanol to obtain 1,3-bis{3-[1-(β-D-ribofuranosyl)-1H-1,2,3-triazol-4-yl]propyl]-6-methyluracil as a first analog of pyrimidine nucleosides containing two D-ribofuranose fragments.
- Subjects
PYRIMIDINE nucleosides; CLICK chemistry; NUCLEOSIDES; BROMOMETHANE
- Publication
Russian Journal of Organic Chemistry, 2020, Vol 56, Issue 1, p181
- ISSN
1070-4280
- Publication type
Article
- DOI
10.1134/S1070428020010285