We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
An Updated Review on Monkeypox Viral Disease: Emphasis on Genomic Diversity.
- Authors
Rabaan, Ali A.; Alasiri, Nada A.; Aljeldah, Mohammed; Alshukairiis, Abeer N.; AlMusa, Zainab; Alfouzan, Wadha A.; Abuzaid, Abdulmonem A.; Alamri, Aref A.; Al-Afghani, Hani M.; Al-baghli, Nadira; Alqahtani, Nawal; Al-baghli, Nadia; Almoutawa, Mashahed Y.; Mahmoud Alawi, Maha; Alabdullah, Mohammed; Bati, Neda A. Al; Alsaleh, Abdulmonem A.; Tombuloglu, Huseyin; Arteaga-Livias, Kovy; Al-Ahdal, Tareq
- Abstract
Monkeypox virus has remained the most virulent poxvirus since the elimination of smallpox approximately 41 years ago, with distribution mostly in Central and West Africa. Monkeypox (Mpox) in humans is a zoonotically transferred disease that results in a smallpox-like disease. It was first diagnosed in 1970 in the Democratic Republic of the Congo (DRC), and the disease has spread over West and Central Africa. The purpose of this review was to give an up-to-date, thorough, and timely overview on the genomic diversity and evolution of a re-emerging infectious disease. The genetic profile of Mpox may also be helpful in targeting new therapeutic options based on genes, mutations, and phylogeny. Mpox has become a major threat to global health security, necessitating a quick response by virologists, veterinarians, public health professionals, doctors, and researchers to create high-efficiency diagnostic tests, vaccinations, antivirals, and other infection control techniques. The emergence of epidemics outside of Africa emphasizes the disease's global significance. Increased monitoring and identification of Mpox cases are critical tools for obtaining a better knowledge of the ever-changing epidemiology of this disease.
- Subjects
WEST Africa; CONGO (Democratic Republic); VIRUS diseases; MONKEYPOX; MEDICAL personnel; GENETIC profile; EMERGING infectious diseases; INFECTIOUS disease transmission
- Publication
Biomedicines, 2023, Vol 11, Issue 7, p1832
- ISSN
2227-9059
- Publication type
Article
- DOI
10.3390/biomedicines11071832