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- Title
Hypertriglyceridemia-Induced Acute Pancreatitis—The Milky Way Constellation—The Seven-Year Experience of a Large Tertiary Centre.
- Authors
Edu, Andrei Vicențiu; Pahomeanu, Mihai Radu; Ghiță, Andreea Irina; Constantinescu, Dalia Ioana; Grigore, Daniela Gabriela; Bota, Andreea Daniela; Luta-Dumitrașcu, Daniela Maria; Țieranu, Cristian George; Negreanu, Lucian
- Abstract
(1) Background: Hypertriglyceridemia (HTG) is a well-known metabolic condition associated with an increased risk of acute pancreatitis. In this study, we tried to establish whether there are any significant disparities concerning recurrence rate, intensive care unit (ICU) admission, hospital (ICU and total) length of stay (LoS), morphology, severity and age between HTG-induced acute pancreatitis and any other known cause of pancreatitis (OAP). (2) Methods: The research was a retrospective unicentric cohort study, using information from the Bucharest Acute Pancreatitis Index (BUC-API) registry, a database of 1855 consecutive cases of acute pancreatitis. (3) Results: We found a weak association between HTG-AP and recurrence. The HTG-AP patients were younger, with a median of 44.5 years, and had a longer ICU stay than the OAP patients. In addition, we identified that the HTG-AP patients were more likely to develop acute peripancreatic fluid collection (APFC), to be admitted in ICU, to have a more severe course of disease and to be cared for in a gastroenterology ward. (4) Conclusions: Hypertriglyceridemia-induced APs have a more severe course. The typical patient with HTG-AP is a middle-aged male, with previous episodes of AP, admitted in the gastroenterology ward, with a longer ICU stay and longer length of hospitalization, more likely to evolve in a severe acute pancreatitis (SAP) and with a higher probability of developing APFC.
- Subjects
MILKY Way; PANCREATITIS; INTENSIVE care units; NECROTIZING pancreatitis; DISEASE progression; CONSTELLATIONS
- Publication
Diagnostics (2075-4418), 2024, Vol 14, Issue 11, p1105
- ISSN
2075-4418
- Publication type
Article
- DOI
10.3390/diagnostics14111105