We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
EVALUATION THE EFFECT AND EFFICACY OF LIDOCAINE ON HEALING OF SKIN WOUND IN RABBITS.
- Authors
Shekho, Hiba Abdulaziz; Wadee, Siham Agmee; Khorsheed Al-bayati, Hassan H.; Ismaeal, Maythaem A.
- Abstract
The current study proceeded on six female rabbits weighing 1600 ± 200 g were used to determine the efficacy of 2% lidocaine (most commonly used concentration) in healing of skin wound. After anesthetized a two full thickness surgical incision were made on two sides of midline in back region of all animals, and divided into two groups randomly. In treated group, the right side were infiltrated with 3 ml of 2% lidocaine; In control group, the left side were infiltrated with 3ml of normal saline. Sites of intervention were estimated by histopathology. This study evidence 2% lidocaine that delay wound healing process and decrease wound strength, formation of blood vessel and other skin content as hair follicle and there muscle.
- Subjects
HEALING; LIDOCAINE; SURGICAL site; HAIR follicles; HEMATOPOIESIS
- Publication
Systematic Reviews in Pharmacy, 2020, Vol 11, Issue 12, p1368
- ISSN
0975-8453
- Publication type
Article