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- Title
Inhibition of Oral Bacterial Growth (Streptococcus Mutans and Porphyromonas Gingivalis) using Black Rice Bran Ethanol Extract (Oryza Sativa L.) as A Natural Mouthwash.
- Authors
Marhamah; Achmad, Harun; Handayani, Hendrastuti; Horax, Sherly; Fajriani; Galib B, Nurhaedah H.; Arief, Sasmita M.
- Abstract
Oral health problems in Indonesia are still relatively high. Indonesian National Health Research 2018 stated that oral health problem’s proportion in Indonesia is 57.6%. Diseases in the oral cavity occur due to accumulation of bacteria, including bacteria that cause dental caries (Streptococcus mutans) and periodontal disease (Porphyromonas gingivalis). Current scientific methods prioritize prevention care to take care of oral health such as teeth brushing regularly using toothpaste and using mouthwash rather than surgical intervention. However, mouthwash contains alcohol, in which can increase the risk of developing oral cancer. Rice bran is a natural comestible containing antibacterial substances. Differences in pigment in rice affect its antibacterial activities. Hence, this research novelty lies in using black rice bran extract (Oryza sativa L.) formulated mouthwash. This study was a laboratory experimental study with post-test only with control group design. The study itself was divided into several phases, extract making to inhibition test. Statistical analysis resulted bran extract with concentration of 10, 20, 40, 80, and 100% with ampicillin positive control each have different inhibition zone and are statistically significant (p<0.05) to Streptococcus mutans (p=0.00) and Porphyromonas gingivalis (p=0.00). Based on study conducted mouthwash A and negative control was used as comparative variables for mouthwash with 10% concentration and shows significance level of 0.00 (p<0.05) which means there is a significant difference between each group. Black Rice Bran extract mouthwash as inhibitor Streptococcus mutans and Porphyromonas gingivalis growth bacteria.
- Publication
Systematic Reviews in Pharmacy, 2020, Vol 11, Issue 5, p666
- ISSN
0975-8453
- Publication type
Article