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- Title
Assessment of the Coupling Between RTapex and RR Interval as an Index of Temporal Dispersion of Ventricular Repolarization.
- Authors
Lombardi, Federico; Colombo, Andrea; Porta, Alberto; Baselli, Giuseppe; Cerutti, Sergio; Fiorentini, Cesare
- Abstract
To evaluate the dynamic characteristics of the relationship between the RT and RR intervals we analyzed the RR/RTapex variability interaction with a dynamic parametric model whose parameters can be directly estimated from the beat-to-beat series RR and RTapex intervals. The model is designed to separate the fraction of RTapex variability driven by RB changes from that independent of RR variations and to quantify the gain and phase of the relationship between RR and RTapex intervals. The percentage of RTapex variability driven by RR variability was significantly greater in young normal subjects in comparison with postmyocardial infarction patients as well as with age-matched control subjects. This new approach based on the quantification of the RTapex variability dependent and independent of beat-to-beat RR interval changes could be used to quantify the degree of uncoupling between the two signals thus providing a new and noninvasive index of temporal dispersion of ventricular repolarization.
- Subjects
HEART beat; HEART conduction system; CARDIOMYOPATHIES; MYOCARDITIS; BLOOD circulation disorders; NECROSIS
- Publication
Pacing & Clinical Electrophysiology, 1998, Vol 21, Issue 11, p2396
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1111/j.1540-8159.1998.tb01189.x