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- Title
Ten-year incidence of post-transplant Diabetes Mellitus in renal transplant patients.
- Authors
Habibnia, Fatemeh; Oliaei, Farshid; Shirafkan, Hoda; Abbasi Firoozjah, Mobarakeh; Rezaei Roshan, Mobina; Akbari, Roghayeh
- Abstract
Background: Kidney transplantation is the treatment of choice for renal failure. Development of New-Onset Diabetes After Transplantation (NODAT) significantly increases kidney graft loss and mortality. This study aimed to evaluate the 10-years prevalence of NODAT in renal transplant patients. Methods: In this cross-sectional study, medical records of non-diabetic patients undergoing kidney transplant in Shahid-Beheshti Hospital of Babol, between March 2009–2019 were retrospectively reviewed. Results: Totally 284 patients with the mean age of 40.83 ± 12.94 years were included. New-Onset Diabetes After Transplantation was identified in 57 (20.1%) patients and 92.98% developed NODAT during the first month after transplantation. New-Onset Diabetes After Transplantation and non-NODAT patients were 43.8% and 34.38% female. Graft rejection occurred in 18 (31%) of NODAT and 78 (34%) of non-NODAT patients (p =.69). Patients with NODAT were about 10 years older (47.88 ± 11.06 vs 38.96 ± 13.12 years; p =.002). The pre-transplant Fasting Blood Sugar (FBS) was higher in the NODAT group (93.78 ± 13.78 vs 87.07 ± 11.56, p =.001) and post-transplantation cytomegalovirus (CMV) infection was higher in NODAT group (56% vs 40%, p =.021). New-Onset Diabetes After Transplantation patients had significantly higher BMI (27.16 ± 5.39 vs 23.94 ± 4.71, p <.001). Conclusion: New-Onset Diabetes After Transplantation is more prevalent in subjects with older age, higher BMI, post-transplant CMV infection, and higher pre-transplant FBS but gender, pre-transplant CMV infection, type of dialysis and smoking were not associated with it. So, these patients should be followed-up more diligently.
- Subjects
KIDNEY transplantation; DIABETES; CYTOMEGALOVIRUS diseases; GRAFT rejection; BLOOD sugar; KIDNEY failure
- Publication
Diabetes & Vascular Disease Research, 2022, Vol 19, Issue 6, p1
- ISSN
1479-1641
- Publication type
Article
- DOI
10.1177/14791641221137352