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- Title
Synthesis of Biodegradable Pyrazole, Pyran, Pyrrole, Pyrimidine and Chromene Derivatives having Medical and Surface Activities.
- Authors
El-Sayed, Refat
- Abstract
In this research, stearic acid and propylene oxide are used to synthesize biodegradable heterocyles (pyrazole, pyran, chromene, and pyrimidine) to improve their solubility and lower their toxicity. The chemical structure of these surfactants was confirmed using IR, 1H, and C NMR spectra. Some of these compounds have higher activity than commercial antibiotics and may be useful in the pharmaceutical industry.
- Subjects
STEARIC acid; HETEROCYCLIC compound derivatives; PYRAZOLES; HETEROCYCLIC compounds synthesis; PYRIMIDINE synthesis; PYRAN synthesis; SURFACE active agents spectra; THERAPEUTICS
- Publication
Journal of Surfactants & Detergents, 2016, Vol 19, Issue 6, p1153
- ISSN
1097-3958
- Publication type
Article
- DOI
10.1007/s11743-016-1881-0