We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Biomarkers for traumatic brain injury: a short review.
- Authors
Gutierre, Marcela Usberti; Telles, João Paulo Mota; Welling, Leonardo Christiaan; Rabelo, Nícollas Nunes; Teixeira, Manoel Jacobsen; Figueiredo, Eberval Gadelha
- Abstract
Cellular response to TBI is a mixture of excitotoxicity, neuroinflammation, and cell death. Biomarkers that can track these lesions and inflammatory processes are being explored for their potential to provide objective measures in the evaluation of TBI, from prehospital care to rehabilitation. By understanding the pathways involved, we could be able to improve diagnostic accuracy, guide management, and prevent long-term disability. We listed some of the recent advances in this translational, intriguing, fast-growing field. Although the knowledge gaps are still significant, some markers are showing promising results and could be helping patients in the near future.
- Subjects
BRAIN injuries; BIOMARKERS; KNOWLEDGE gap theory; NEUROINFLAMMATION; INFLAMMATION
- Publication
Neurosurgical Review, 2021, Vol 44, Issue 4, p2091
- ISSN
0344-5607
- Publication type
Article
- DOI
10.1007/s10143-020-01421-0