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- Title
HEMATOLOJİ KLİNİĞİNE BAŞVURAN HASTALARDA DERMATOLOJİK BULGULARIN DEĞERLENDİRİLMESİ: 2 YILLIK KESİTSEL BİR ÇALIŞMA.
- Authors
AKIN BELLİ, Aslı; KARA POLAT, Asude; KARAKUŞ, Volkan
- Abstract
Objective There are a few studies regarding the frequency of skin findings in hematological diseases reported from our country. We aimed to investigate the prevalence of dermatological findings in patients who were followed up at the Hematology outpatient clinic of our hospital with this study. Materials and Methods A cross-sectional study involving 217 patients who were followed up at the Hematology outpatient clinic of our hospital between February 2014-June 2016 was conducted. Hematologic disease diagnoses, disease duration, follow-up period, dermatological examination data obtained with dermatology consultation, and presence of any other malignancy were retrospectively reviewed from the patient file records. Results Of 217 patients (102 female, 115 male), the mean age was 63.06±14.7 years. The mean duration of hematologic disease was 27.98±35.9 months and the mean duration of disease follow-up was 12.21±6.65 months. The most common skin findings were purpura (95% GA, 7.4%-16.1%), pruritus (9.7%, 95% GA, 6%-13.8%), and viral infections (5.1%, 95% GA, 2.3%-8.3%), respectively. In two patients with myelodysplastic syndrome, thalidomide- and deferasirox-associated vasculitic drug reactions were observed From specific cutaneous infiltrations, cutaneous leukemia was found in a patient with chronic lymphocytic leukemia and granulocytic sarcoma in a patient with acute myeloid leukemia. Conclusion Skin findings are quite common and have a wide variety in hematologic patients with frequent immunsupression and multiple drug use. Because skin findings of hematologic diseases can be a sign of serious infection, drug reaction, or cutaneous spread of the disease, diagnosis and treatment of these diseases have prognostic significance.
- Publication
Medical Journal of Suleyman Demirel University, 2019, Vol 26, Issue 3, p264
- ISSN
1300-7416
- Publication type
Article
- DOI
10.17343/sdutfd.446587