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Factors affecting 1h NMR spectra of blood plasma: cancer, diet and freezing.
Published in:
NMR in Biomedicine, 1988, v. 1, n. 2, p. 90, doi. 10.1002/nbm.1940010206
By:
- Bell, J. D.;
- Brown, J. C. C.;
- Norman, R. E.;
- Sadler, P. J.;
- Newell, D. R.
Publication type:
Article
Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma.
Published in:
2014
By:
- Chen, L;
- Zhao, Y;
- Halliday, G C;
- Berry, P;
- Rousseau, R F;
- Middleton, S A;
- Nichols, G L;
- Del Bello, F;
- Piergentili, A;
- Newell, D R;
- Lunec, J;
- Tweddle, D A
Publication type:
journal article
Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma.
Published in:
British Journal of Cancer, 2014, v. 111, n. 4, p. 716, doi. 10.1038/bjc.2014.325
By:
- Chen, L;
- Zhao, Y;
- Halliday, G C;
- Berry, P;
- Rousseau, R F;
- Middleton, S A;
- Nichols, G L;
- Del Bello, F;
- Piergentili, A;
- Newell, D R;
- Lunec, J;
- Tweddle, D A
Publication type:
Article
The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition.
Published in:
British Journal of Cancer, 2012, v. 106, n. 8, p. 1386, doi. 10.1038/bjc.2012.70
By:
- Haagensen, E J;
- Kyle, S;
- Beale, G S;
- Maxwell, R J;
- Newell, D R
Publication type:
Article
Thiothymidine combined with UVA as a potential novel therapy for bladder cancer.
Published in:
2011
By:
- Pridgeon, S. W.;
- Heer, R.;
- Taylor, G. A.;
- Newell, D. R.;
- O'Toole, K.;
- Robinson, M.;
- Xu, Y.-Z.;
- Karran, P.;
- Boddy, A. V.
Publication type:
journal article
Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells.
Published in:
2010
By:
- Johnson, N.;
- Bentley, J.;
- Wang, L.-Z.;
- Newell, D. R.;
- Robson, C. N.;
- Shapiro, G. I.;
- Curtin, N. J.
Publication type:
journal article
A study of amsalog (CI-921) administered orally on a 5-day schedule, with bioavailability and pharmacokinetically guided dose escalation.
Published in:
2002
By:
- Fyfe, D.;
- Raynaud, F.;
- Langley, R.;
- Newell, D.;
- Halbert, G.;
- Gardner, C.;
- Clayton, K.;
- Woll, P.;
- Judson, I.;
- Carmichael, J.;
- Langley, R E;
- Newell, D R;
- Woll, P J
Publication type:
journal article
Editorial Expression of Concern: Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells.
Published in:
2024
By:
- Johnson, N.;
- Bentley, J.;
- Wang, L-Z;
- Newell, D. R.;
- Robson, C. N.;
- Shapiro, G. I.;
- Curtin, N. J.
Publication type:
Correction Notice
Pharmacokinetics of high dose methylprednisolone and use in hematological malignancies.
Published in:
Hematological Oncology, 1993, v. 11, n. 2, p. 89, doi. 10.1002/hon.2900110206
By:
- Patel, P. M.;
- Selby, P. J.;
- Graham, M. A.;
- Viner, C.;
- Newell, D. R.;
- McElwain, T. J.
Publication type:
Article
Pharmacokinetics of high dose methylprednisolone and use in hematological malignancies.
Published in:
1993
By:
- Patel, P M;
- Selby, P J;
- Graham, M A;
- Viner, C;
- Newell, D R;
- McElwain, T J
Publication type:
journal article
The myelotoxicity of carboplatin is influenced by the time of its administration.
Published in:
1990
By:
- Kerr, D. J.;
- Lewis, C.;
- O'Neil, B.;
- Lawson, N.;
- Blackie, R. G.;
- Newell, D. R.;
- Boxall, F.;
- Cox, J.;
- Rankin, E. M.;
- Kaye, S. B.
Publication type:
journal article
19F nuclear magnetic resonance imaging of drug distribution in vivo: The disposition of an antifolate anticancer drug in mice.
Published in:
Magnetic Resonance in Medicine, 1991, v. 17, n. 1, p. 189, doi. 10.1002/mrm.1910170122
By:
- Maxwell, R. J.;
- Frenkiel, T. A.;
- Newell, D. R.;
- Bauer, C.;
- Griffiths, J. R.
Publication type:
Article
Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK.
Published in:
2003
By:
- Newell, D R;
- Searle, K M;
- Westwood, N B;
- Burtles, S S;
- Cancer Research UK Phase I/II Clinical Trials Committee
Publication type:
Biography
Induction of apoptosis by the ADEPT agent ZD2767: comparison with the classical nitrogen mustard chlorambucil and a monofunctional ZD2767 analogue.
Published in:
British Journal of Cancer, 2001, v. 85, n. 5, p. 764, doi. 10.1054/bjoc.2001.1947
By:
- Monks, N R;
- Blakey, D C;
- Curtin, N J;
- East, S J;
- Heuze, A;
- Newell, D R
Publication type:
Article
Flasks, fibres and flanks – pre-clinical tumour models for predicting clinical antitumour activity.
Published in:
2001
By:
- Newell, D R
Publication type:
Editorial
A phase I study of nolatrexed dihydrochloride in children with advanced cancer. A United Kingdom Children’s Cancer Study Group Investigation.
Published in:
British Journal of Cancer, 2001, v. 84, n. 1, p. 11, doi. 10.1054/bjoc.2000.1569
By:
- Estlin, E J;
- Pinkerton, C R;
- Lewis, I J;
- Lashford, L;
- McDowell, H;
- Morland, B;
- Kohler, J;
- Newell, D R;
- Boddy, A V;
- Taylor, G A;
- Price, L;
- Ablett, S;
- Hobson, R;
- Pitsiladis, M;
- Brampton, M;
- Clendeninn, N;
- Johnston, A;
- Pearson, A D J
Publication type:
Article
Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro.
Published in:
British Journal of Cancer, 2001, v. 84, n. 1, p. 106, doi. 10.1054/bjoc.2000.1555
By:
- Bowman, K J;
- Newell, D R;
- Calvert, A H;
- Curtin, N J
Publication type:
Article
Cellular glutathione as a determinant of the sensitivity of colorectal tumour cell-lines to ZD2767 antibody-directed enzyme prodrug therapy (ADEPT).
Published in:
British Journal of Cancer, 2000, v. 83, n. 2, p. 267, doi. 10.1054/bjoc.2000.1240
By:
- Monks, N R;
- Calvete, J A;
- Curtin, N J;
- Blakey, D C;
- East, S J;
- Newell, D R
Publication type:
Article
Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, ThymitaqTM) and paclitaxel.
Published in:
British Journal of Cancer, 2000, v. 82, n. 9, p. 1519
By:
- Hughes, A N;
- Griffin, M J;
- Newell, D R;
- Calvert, A H;
- Johnston, A;
- Kerr, B;
- Lee, C;
- Liang, B;
- Boddy, A V
Publication type:
Article
Dipyridamole potentiates the in vitro activity of MTA (LY231514) by inhibition of thymidine transport.
Published in:
British Journal of Cancer, 2000, v. 82, n. 4, p. 924, doi. 10.1054/bjoc.1999.1020
By:
- Smith, P G;
- Marshman, E;
- Newell, D R;
- Curtin, N J
Publication type:
Article
Evaluation of rodent-only toxicology for early clinical trials with novel cancer therapeutics.
Published in:
British Journal of Cancer, 1999, v. 81, n. 5, p. 760, doi. 10.1038/sj.bjc.6690761
By:
- Newell, D R;
- Burtles, S S;
- Fox, B W;
- Jodrell, D I;
- Connors, T A
Publication type:
Article
Potentiation of the cytotoxicity of thymidylate synthase (TS) inhibitors by dipyridamole analogues with reduced α1-acid glycoprotein binding.
Published in:
British Journal of Cancer, 1999, v. 80, n. 11, p. 1738, doi. 10.1038/sj.bjc.6690591
By:
- Curtin, N J;
- Bowman, K J;
- Turner, R N;
- Huang, B;
- Loughlin, P J;
- Calvert, A H;
- Golding, B T;
- Griffin, R J;
- Newell, D R
Publication type:
Article
Application of Flow Microcalorimetry to Analytical Problems: the Preparation, Storage and Assay of Frozen Inocula of Saccharomyces cerevisiae.
Published in:
Journal of Applied Microbiology, 1976, v. 41, n. 2, p. 197, doi. 10.1111/j.1365-2672.1976.tb00620.x
By:
- BEEZER, A. E.;
- NEWELL, R. D.;
- TYRRELL, H. J. V.
Publication type:
Article

Found: 23

Factors affecting <sup>1</sup>h NMR spectra of blood plasma: cancer, diet and freezing.

Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma.

Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma.

The synergistic interaction of MEK and PI3K inhibitors is modulated by mTOR inhibition.

Thiothymidine combined with UVA as a potential novel therapy for bladder cancer.

Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells.

A study of amsalog (CI-921) administered orally on a 5-day schedule, with bioavailability and pharmacokinetically guided dose escalation.

Editorial Expression of Concern: Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells.

Pharmacokinetics of high dose methylprednisolone and use in hematological malignancies.

Pharmacokinetics of high dose methylprednisolone and use in hematological malignancies.

The myelotoxicity of carboplatin is influenced by the time of its administration.

<sup>19</sup>F nuclear magnetic resonance imaging of drug distribution in vivo: The disposition of an antifolate anticancer drug in mice.

Professor Tom Connors and the development of novel cancer therapies by the Phase I/II Clinical Trials Committee of Cancer Research UK.

Induction of apoptosis by the ADEPT agent ZD2767: comparison with the classical nitrogen mustard chlorambucil and a monofunctional ZD2767 analogue.

Flasks, fibres and flanks – pre-clinical tumour models for predicting clinical antitumour activity.

A phase I study of nolatrexed dihydrochloride in children with advanced cancer. A United Kingdom Children’s Cancer Study Group Investigation.

Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro.

Cellular glutathione as a determinant of the sensitivity of colorectal tumour cell-lines to ZD2767 antibody-directed enzyme prodrug therapy (ADEPT).

Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, Thymitaq<sup>TM</sup>) and paclitaxel.

Dipyridamole potentiates the in vitro activity of MTA (LY231514) by inhibition of thymidine transport.

Evaluation of rodent-only toxicology for early clinical trials with novel cancer therapeutics.

Potentiation of the cytotoxicity of thymidylate synthase (TS) inhibitors by dipyridamole analogues with reduced α<sub>1</sub>-acid glycoprotein binding.

Application of Flow Microcalorimetry to Analytical Problems: the Preparation, Storage and Assay of Frozen Inocula of Saccharomyces cerevisiae.