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- Title
Synthesis of Some Indolyl Derivatives under Solvent Free Conditions, Their Cytotoxicity, and DNA Cleavage Studies.
- Authors
Rathod, A. S.; Biradar, J. S.
- Abstract
A one-pot, rapid, facile, green, and efficient method of synthesis of pyran fused indolyl and 1,3-dicarbonyl analogs has been carried out under the conventional and also solvent-free conditions involving MW irradiation. The structures of products have been confirmed by spectral data. All products have been tested for DNA cleavage and in vitro cytotoxicity against three tumor cell lines. Some products are characterized by high activity.
- Subjects
PYRAN synthesis; DNA; CELL lines; DNA synthesis
- Publication
Russian Journal of General Chemistry, 2020, Vol 90, Issue 1, p135
- ISSN
1070-3632
- Publication type
Article
- DOI
10.1134/S1070363220010211