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- Title
Evaluation of the Cardiovascular Effects of Coriandrum sativum and Citrus limon to Treat Arsenic-Induced Endothelial Damage and Hypertension in Rats.
- Authors
Rana, Reemal; Mehmood, Malik Hassan; Shaukat, Bushra; Shahid, Sidra; Malik, Abdul; Murtaza, Babar
- Abstract
H and E staining of liver tissue of normal (A), diseased (B), Positive control (C), I C. sativum i high dose (D), I C. limon i high dose (E), low dose combination (F) and high dose combination (G). When tested for chronic administration of I C. sativum i , I C. limon i and their combinations of low doses and high doses in arsenic-induced hypertensive rats, CS alone and in combination (CS and CL) in high doses significantly (P < 0.001) decreased the blood pressure as shown in Figure 3. 3.7. H and E staining of kidney tissue of normal (A), diseased (B), Positive control (C), I C. sativum i high dose (D), I C. limon i high dose (E), low dose combination (F) and high dose combination (G). Conclusions This study establishes that I C. sativum i and I C. limon i treatments mitigate arsenic-induced hypertension and arsenic-mediated oxidative stress, possibly through their endothelium-protective, and anti-oxidant activities.
- Subjects
LEMON; CORIANDER; PHENOLIC acids; ISOFLURANE; CALCIUM channels; HYPERTENSION
- Publication
Life (2075-1729), 2022, Vol 12, Issue 11, p1842
- ISSN
2075-1729
- Publication type
Article
- DOI
10.3390/life12111842