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- Title
New insights into the burden and costs of multiple sclerosis in Europe: Results of the Czech Republic.
- Authors
Havrdova, Eva; Kobelt, Gisela; Berg, Jenny; Capsa, Daniela; Gannedahl, Mia; Doležal, Tomáš
- Abstract
Introduction: In order to estimate the value of interventions in multiple sclerosis (MS) – where lifetime costs and outcomes cannot be observed – outcome data have to be combined with costs. This requires that cost data be regularly updated. Objectives and methods: This study is part of a cross-sectional retrospective study in 16 countries collecting data on resource consumption and work capacity, health-related quality of life (HRQoL) and prevalent symptoms for patients with MS. Descriptive analyses are presented by level of severity, in the societal perspective, in CZK 2015. Results: A total of 747 patients (mean age 47 years) participated; 86% were below retirement age and of these, 49% were employed. Employment was related to disease severity, and MS affected productivity at work for 82% of those working. Overall, 92% and 66% of patients experienced fatigue and cognitive difficulties as a problem. Mean utility and annual costs were 0.832 and 257,000CZK at Expanded Disability Status Scale (EDSS) 0–3, 0.530 and 425,500CZK at EDSS 4–6.5 and 0.141 and 489,000CZK at EDSS 7–9. The average cost of a relapse was estimated at 12,600CZK. Conclusion: This study provides current data on MS in the Czech Republic that are important for the development of health policies.
- Subjects
CZECH Republic; MULTIPLE sclerosis research; WORK capacity evaluation; QUALITY of life; MULTIPLE sclerosis; COGNITION disorders; FATIGUE (Physiology); HEALTH policy; PATIENTS
- Publication
Multiple Sclerosis Journal, 2017, Vol 23, p41
- ISSN
1352-4585
- Publication type
Article
- DOI
10.1177/1352458517708117