Title

HYALURONIC ACID AND SKIN: WOUND HEALING AND AGING.

Authors

Manuskiatti, Woraphong; Maibach, Howard I.

Abstract

Hyaluronic acid (HA), isolated from the vitreous body of the bovine eye in 1934, derives its name from the tissue in which it was found and one of its constituent sugars. Total HA content has been estimated to be about 15g in an adult man; approximately one-third turns over daily. HA, a high-molecular weight polysaccharide, is a glycosaminoglycan, synthesized in the plasma membrane of fibroblasts and other cells, with a structure consisting of a 200 to 10,000 linear polyanionic polymer of repeating disaccharide units.

Subjects

HYALURONIC acid; POLYSACCHARIDES; GLYCOSAMINOGLYCANS; FIBROBLASTS; CARBOHYDRATES; POLYMERS

Publication

International Journal of Dermatology, 1996, Vol 35, Issue 8, p539

ISSN

0011-9059

Publication type

Academic Journal

DOI

10.1111/j.1365-4362.1996.tb03650.x