We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Adenosine Deaminase in the Congenitally Immunodeficient Nude Mouse.
- Authors
Körber, W.; Hermann, G.
- Abstract
Various cases of human combined immunodeficiency together with adenosine-deaminase deficiency have been described in the last 3 years. The congenitally thymus-less (nu/nu) mouse could be presumed to serve as a possible laboratory model for examination of this combination of enzymatic deficiency and immunodeficiency. The present investigations, however, show similar isozyme pattern and enzymatic activity of nude mice and healthy Balb/c and C3H mice. Adenosine-deaminase deficiency cannot be the cause of the immunodeficiency of the nude mouse.
- Subjects
IMMUNODEFICIENCY; ENDOCRINE glands; LYMPHOID tissue; ADENINE; IMMUNITY; IMMUNOSUPPRESSION
- Publication
Scandinavian Journal of Immunology, 1974, Vol 3, Issue 6, p837
- ISSN
0300-9475
- Publication type
Article
- DOI
10.1111/j.1365-3083.1974.tb01320.x