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- Title
Comet assay application in evaluation the safe use of medicinal plants.
- Authors
Mohamed, Ana Mariel; Cangiano, María Alejandra; Alcaráz, Lucía Esther; Satorres, Sara Elena; Laciar, Analía Liliana; Mattana, Claudia Maricel
- Abstract
Genotoxicity of three aqueous extracts obtained of Acacia cavens (espinillo), Acacia furcatispina (garabato) and Prosopis torquata (tintitaco), was evaluated by comet assay. Three Concentrations (0.1, 10 and 20 mg/mL to A. cavens and A. furcatispina; 0.2, 2 and 20 mg/mL to P. torquata) were tested and the damage index for each was calculated. Based on the results, it was determined that both aqueous extracts of A. cavens and A. furcatispina showed no damage DNA at 0.1 and 10 mg/mL but, at 20 mg/mL induced DNA damage (p< 0.05), showing moderate level damage (category 2). On the other hand, P. torquata extract was strongly genotoxic at all concentrations tested.
- Subjects
MEDICINAL plants; EFFECT of poisons on plants; PLANT genetics; PLANT extracts; ACACIA; MESQUITE
- Publication
Emirates Journal of Food & Agriculture (EJFA), 2016, Vol 28, Issue 10, p737
- ISSN
2079-052X
- Publication type
Article
- DOI
10.9755/ejfa.2016-06-669