We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Antimony to Cure Visceral Leishmaniasis Unresponsive to Liposomal Amphotericin B.
- Authors
Morizot, Gloria; Jouffroy, Romain; Faye, Albert; Chabert, Paul; Belhouari, Katia; Calin, Ruxandra; Charlier, Caroline; Miailhes, Patrick; Siriez, Jean-Yves; Mouri, Oussama; Yera, Hélène; Gilquin, Jacques; Tubiana, Roland; Lanternier, Fanny; Mamzer, Marie-France; Legendre, Christophe; Peyramond, Dominique; Caumes, Eric; Lortholary, Olivier; Buffet, Pierre
- Abstract
We report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-threatening adverse events and resulted in rapid and sustained clinical and parasitological cure.
- Subjects
THERAPEUTIC use of antimony; VISCERAL leishmaniasis; AMPHOTERICIN B; CYTOMEGALOVIRUS diseases; IMMUNOSUPPRESSION; POLYMERASE chain reaction; THERAPEUTICS
- Publication
PLoS Neglected Tropical Diseases, 2016, Vol 10, Issue 1, p1
- ISSN
1935-2727
- Publication type
Article
- DOI
10.1371/journal.pntd.0004304