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- Title
Diagnosis of leishmaniasis.
- Authors
Elmahallawy, Ehab Kotb; Sampedro Martínez, Antonio; Rodriguez-Granger, Javier; Hoyos-Mallecot, Yannick; Agil, Ahmad; Navarro Mari, José Marí; Gutierrez Fernández, José
- Abstract
Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical ( not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifestations depends on the immune status of the host, on the parasite, and on immunoinflammatory responses. Visceral leishmaniasis causes high morbidity and mortality in the developing world. Reliable laboratory methods become mandatory for accurate diagnosis, especially in immunocompromised patients such as those infected with HIV. In this article, we review the current state of the diagnostic tools for leishmaniasis, especially the serological test.
- Subjects
LEISHMANIASIS diagnosis; PROTOZOAN diseases; PARASITIC diseases; LEISHMANIA; IMMUNE response; IMMUNOCOMPROMISED patients
- Publication
Journal of Infection in Developing Countries, 2014, Vol 8, Issue 8, p961
- ISSN
2036-6590
- Publication type
Article
- DOI
10.3855/jidc.4310