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Oncogenic function of the MUC1 receptor subunit in gene regulation.
Published in:
Oncogene, 2010, v. 29, n. 42, p. 5663, doi. 10.1038/onc.2010.334
By:
- Kufe, D
Publication type:
Article
Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
Published in:
Oncogene, 2010, v. 29, n. 6, p. 920, doi. 10.1038/onc.2009.391
By:
- Khodarev, N.;
- Ahmad, R.;
- Rajabi, H.;
- Pitroda, S.;
- Kufe, T.;
- McClary, C.;
- Joshi, M. D.;
- MacDermed, D.;
- Weichselbaum, R.;
- Kufe, D.
Publication type:
Article
Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers.
Published in:
Cancer Gene Therapy, 2009, v. 16, n. 8, p. 609, doi. 10.1038/cgt.2009.37
By:
- Weichselbaum, R. R.;
- Kufe, D.
Publication type:
Article
Translational strategies exploiting TNF-α that sensitize tumors to radiation therapy.
Published in:
Cancer Gene Therapy, 2009, v. 16, n. 4, p. 373, doi. 10.1038/cgt.2008.86
By:
- Mauceri, H. J.;
- Beckett, M. A.;
- Liang, H.;
- Sutton, H. G.;
- Pitroda, S.;
- Galka, E.;
- Efimova, E.;
- Darga, T.;
- Khodarev, N. N.;
- King, C. R.;
- Posner, M. C.;
- Hellman, S.;
- Kufe, D. W.;
- Weichselbaum, R. R.
Publication type:
Article
Ionizing radiation: a genetic switch for cancer therapy.
Published in:
Cancer Gene Therapy, 2006, v. 13, n. 1, p. 1, doi. 10.1038/sj.cgt.7700879
By:
- Mezhir, J. J.;
- Smith, K. D.;
- Posner, M. C.;
- Senzer, N.;
- Yamini, B.;
- Kufe, D. W.;
- Weichselbaum, R. R.
Publication type:
Article
MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90.
Published in:
Oncogene, 2006, v. 25, n. 1, p. 20, doi. 10.1038/sj.onc.1209012
By:
- Ren, J.;
- Bharti, A.;
- Raina, D.;
- Chen, W.;
- Ahmad, R.;
- Kufe, D.
Publication type:
Article
Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model.
Published in:
Gene Therapy, 2003, v. 10, n. 3, p. 206, doi. 10.1038/sj.gt.3301867
By:
- Gupta, V K;
- Park, J O;
- Kurihara, T;
- Koons, A;
- Mauceri, H J;
- Jaskowiak, N T;
- Kufe, D W;
- Weichselbaum, R R;
- Posner, M C
Publication type:
Article
Selection and characterization of MUC1-specific CD8<sup>+</sup> T cells from MUC1 transgenic mice immunized with dendritic-carcinoma fusion cells.
Published in:
Immunology, 2000, v. 101, n. 3, p. 316, doi. 10.1046/j.1365-2567.2000.00101.x
By:
- Gong, J.;
- Apostolopoulos, V.;
- Chen, D.;
- Chen, H.;
- Koido, S.;
- Gendler, S. J.;
- Mckenzie, I. F.;
- Kufe, D.
Publication type:
Article
Human cancer and animal viral oncology.
Published in:
Cancer (0008543X), 1974, v. 34, n. S8, p. 1406, doi. 10.1002/1097-0142(197410)34:8+<1406::AID-CNCR2820340812>3.0.CO;2-R
By:
- Spiegelman, S.;
- Axel, R.;
- Baxt, W.;
- Kufe, D.;
- Schlom, J.
Publication type:
Article
Immune reconstitution following high-dose chemotherapy with stem cell rescue in patients with advanced breast cancer.
Published in:
Bone Marrow Transplantation, 2000, v. 26, n. 2, p. 169, doi. 10.1038/sj.bmt.1702474
By:
- Avigan, D;
- Wu, Z;
- Joyce, R;
- Elias, A;
- Richardson, P;
- McDermott, D;
- Levine, J;
- Kennedy, L;
- Giallombardo, N;
- Hurley, D;
- Gong, J;
- Kufe, D
Publication type:
Article
Adenoviral TNF-α gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
Published in:
Gene Therapy, 1998, v. 5, n. 3, p. 293, doi. 10.1038/sj.gt.3300594
By:
- Staba, M-J;
- Mauceri, H J;
- Kufe, D W;
- Hallahan, D E;
- Weichselbaum, R R
Publication type:
Article
Induction of antigen-specific antitumor immunity with adenovirus-transduced dendritic cells.
Published in:
Gene Therapy, 1997, v. 4, n. 10, p. 1023, doi. 10.1038/sj.gt.3300496
By:
- Gong, J;
- Chen, L;
- Chen, D;
- Kashiwaba, M;
- Manome, Y;
- Tanaka, T;
- Kufe, D
Publication type:
Article
Requirement of spermidine for induction of both heme synthesis and globin transcription in murine erythroleukemia cells.
Published in:
Journal of Cellular Physiology, 1985, v. 122, n. 3, p. 435, doi. 10.1002/jcp.1041220314
By:
- Watanabe, T.;
- Shafman, T.;
- Kufe, D. W.
Publication type:
Article
Triterpenoid CDDO-Im downregulates PML/RARα expression in acute promyelocytic leukemia cells.
Published in:
Cell Death & Differentiation, 2005, v. 12, n. 5, p. 523, doi. 10.1038/sj.cdd.4401574
By:
- Ikeda, T.;
- Kimura, F;
- Nakata, Y.;
- Sato, K.;
- Ogura, K.;
- Motoyoshi, K.;
- Sporn, M.;
- Kufe, D.
Publication type:
Article
Mitochondrial targeting of JNK/SAPK in the phorbol ester response of myeloid leukemia cells.
Published in:
Cell Death & Differentiation, 2001, v. 8, n. 8, p. 794, doi. 10.1038/sj.cdd.4400886
By:
- Ito, Y;
- Mishra, N C;
- Yoshida, K;
- Kharbanda, S;
- Saxena, S;
- Kufe, D
Publication type:
Article
Localization of tumor-associated glycoprotein DF3 in normal, inflammatory, and neoplastic lesions of the colon.
Published in:
1993
By:
- Andrews, Charles W.;
- Jessup, J. Milburn;
- Goldman, Harvey;
- Hayes, Daniel F.;
- Kufe, Donald W.;
- O'Hara, Carl J.;
- Steele, Glenn D.;
- Andrews, C W Jr;
- Jessup, J M;
- Goldman, H;
- Hayes, D F;
- Kufe, D W;
- O'Hara, C J;
- Steele, G D Jr
Publication type:
journal article
Coordinate elevation of serum markers in ovarian cancer but not in benign disease.
Published in:
1991
By:
- Bast, R. C.;
- Knauf, S.;
- Epenetos, A.;
- Dhokia, B.;
- Daly, L.;
- Tanner, M.;
- Soper, J.;
- Creasman, W.;
- Gall, S.;
- Knapp, R. C.;
- Zurawski, V. R.;
- Schlom, J.;
- Kufe, D. W.;
- Ritts, R. E.;
- Bast, R C Jr
Publication type:
journal article
Immunomodulatory effects of vitamin D: implications for GVHD.
Published in:
Bone Marrow Transplantation, 2010, v. 45, n. 9, p. 1463, doi. 10.1038/bmt.2009.366
By:
- Rosenblatt, J;
- Bissonnette, A;
- Ahmad, R;
- Wu, Z;
- Vasir, B;
- Stevenson, K;
- Zarwan, C;
- Keefe, W;
- Glotzbecker, B;
- Mills, H;
- Joyce, R;
- Levine, J D;
- Tzachanis, D;
- Boussiotis, V;
- Kufe, D;
- Avigan, D
Publication type:
Article
Cancer immunotherapy by fusions of dendritic and tumour cells and rh-IL-12.
Published in:
European Journal of Clinical Investigation, 2005, v. 35, n. 4, p. 279, doi. 10.1111/j.1365-2362.2005.01494.x
By:
- Homma, S.;
- Kikuchi, T.;
- Ishiji, N.;
- Ochiai, K.;
- Takeyama, H.;
- Saotome, H.;
- Sagawa, Y.;
- Hara, E.;
- Kufe, D.;
- Ryan, J. L.;
- Ohno, T.;
- Toda, G.
Publication type:
Article
Immature dendritic cell/tumor cell fusions induce potent antitumour immunity.
Published in:
European Journal of Clinical Investigation, 2003, v. 33, n. 10, p. 897, doi. 10.1046/j.1365-2362.2003.01194.x
By:
- Takeda, A.;
- Homma, S.;
- Okamoto, T.;
- Kufe, D.;
- Ohno, T.
Publication type:
Article
Preventive antitumor activity against hepatocellular carcinoma (HCC) induced by immunization with fusions of dendritic cells and HCC cells in mice.
Published in:
2001
By:
- Homma, Sadamu;
- Toda, Gotaro;
- Gong, Jianlin;
- Kufe, Donald;
- Ohno, Tsuneya;
- Homma, S;
- Toda, G;
- Gong, J;
- Kufe, D;
- Ohno, T
Publication type:
journal article
MUC1-C activates the TAK1 inflammatory pathway in colon cancer.
Published in:
Oncogene, 2015, v. 34, n. 40, p. 5187, doi. 10.1038/onc.2014.442
By:
- Takahashi, H;
- Jin, C;
- Rajabi, H;
- Pitroda, S;
- Alam, M;
- Ahmad, R;
- Raina, D;
- Hasegawa, M;
- Suzuki, Y;
- Tagde, A;
- Bronson, R T;
- Weichselbaum, R;
- Kufe, D
Publication type:
Article
Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells.
Published in:
Oncogene, 2014, v. 33, n. 26, p. 3422, doi. 10.1038/onc.2013.308
By:
- Raina, D;
- Uchida, Y;
- Kharbanda, A;
- Rajabi, H;
- Panchamoorthy, G;
- Jin, C;
- Kharbanda, S;
- Scaltriti, M;
- Baselga, J;
- Kufe, D
Publication type:
Article
MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition.
Published in:
Oncogene, 2014, v. 33, n. 13, p. 1680, doi. 10.1038/onc.2013.114
By:
- Rajabi, H;
- Alam, M;
- Takahashi, H;
- Kharbanda, A;
- Guha, M;
- Ahmad, R;
- Kufe, D
Publication type:
Article
Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein.
Published in:
Oncogene, 2013, v. 32, n. 17, p. 2179, doi. 10.1038/onc.2012.236
By:
- Jin, C;
- Rajabi, H;
- Rodrigo, C M;
- Porco, J A;
- Kufe, D
Publication type:
Article
MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.
Published in:
Oncogene, 2013, v. 32, n. 9, p. 1073, doi. 10.1038/onc.2012.158
By:
- Kufe, D W
Publication type:
Article
Phase I clinical trial of 7-cyanoquinocarcinol (DX-52-1) in adult patients with refractory solid malignancies.
Published in:
2001
By:
- Bunnell, Craig A.;
- Supko, Jeffrey G.;
- Eder Jr., Joseph Paul;
- Clark, Jeffrey W.;
- Lynch, Thomas J.;
- Kufe, Donald W.;
- Shulman, Lawrence N.;
- Bunnell, C A;
- Supko, J G;
- Eder, J P Jr;
- Clark, J W;
- Lynch, T J;
- Kufe, D W;
- Shulman, L N
Publication type:
journal article
A phase I clinical and pharmacokinetic study of the dolastatin analogue cemadotin administered as a 5-day continuous intravenous infusion.
Published in:
2000
By:
- Supko, Jeffrey G.;
- Lynch, Thomas J.;
- Clark, Jeffrey W.;
- Fram, Robert;
- Allen, Lee F.;
- Velagapudi, Raja;
- Kufe, Donald W.;
- Eder Jr, Joseph Paul;
- Supko, J G;
- Lynch, T J;
- Clark, J W;
- Fram, R;
- Allen, L F;
- Velagapudi, R;
- Kufe, D W;
- Eder, J P Jr
Publication type:
journal article
Partial characterization of human leukemia U-937 cell sublines resistant to 9-nitrocamptothecin P.
Published in:
European Journal of Haematology, 1994, v. 53, n. 3, p. 135, doi. 10.1111/j.1600-0609.1994.tb00661.x
By:
- Pantazis, Panayotis;
- Mendoza, J. T.;
- DeJesus, A.;
- Rubin, E.;
- Kufe, D.;
- Giovanella, B. C.
Publication type:
Article
Effect of high-dose thymidine infusions in patients with mycosis fungoides.
Published in:
1981
By:
- Kufe, D. W.;
- Wick, M. M.;
- Moschella, S.;
- Major, P.
Publication type:
journal article

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